Thuy A V Pham1, Dinh D Le2. 1. Department of Periodontology, Faculty of Odonto-Stomatology, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam. 2. Faculty of Odonto-Stomatology, Northern Mountainous Region General Hospital, Quang Nam Province, Vietnam.
Abstract
OBJECTIVES: To determine the dental status and salivary characteristics and to analyse the correlation between creatinine clearance with DMFT index and salivary flow rate in Vietnamese patients with chronic kidney disease (CKD). METHODS: This study was conducted on 111 CKD and 109 non-CKD patients. The socio-demographic characteristics associated with dental habits and xerostomia status were recorded from a self-administered questionnaire. Dental status (DT, MT, FT) and salivary characteristics (flow rate; pH; buffering capacity; urea and creatinine concentrations) were examined. The multivariate regression models were used to assess the correlation of creatinine clearance with DMFT index and salivary flow rate with adjustment for confounders. RESULTS: Patients with CKD made MT and DMFT indices significantly higher than non-CKD subjects. Chronic kidney disease patients had reduced salivary flow rate; but higher xerostomia level, salivary pH and buffering capacity than those in non-CKD subjects. Results of multivariate regression models showed that with lower creatinine clearance 1 mL/min, DMF index was higher 0.02 teeth, and salivary flow rate lower 0.003 mL/min. CONCLUSIONS: There were no differences in dental status between patients with CKD and those without CKD, except that poor renal function is directly related with a higher DMFT index and lower salivary flow rate. Dental professionals should pay greater attention to oral problems during the progression of CKD to prevent deterioration of oral health.
OBJECTIVES: To determine the dental status and salivary characteristics and to analyse the correlation between creatinine clearance with DMFT index and salivary flow rate in Vietnamese patients with chronic kidney disease (CKD). METHODS: This study was conducted on 111 CKD and 109 non-CKD patients. The socio-demographic characteristics associated with dental habits and xerostomia status were recorded from a self-administered questionnaire. Dental status (DT, MT, FT) and salivary characteristics (flow rate; pH; buffering capacity; urea and creatinine concentrations) were examined. The multivariate regression models were used to assess the correlation of creatinine clearance with DMFT index and salivary flow rate with adjustment for confounders. RESULTS:Patients with CKD made MT and DMFT indices significantly higher than non-CKD subjects. Chronic kidney diseasepatients had reduced salivary flow rate; but higher xerostomia level, salivary pH and buffering capacity than those in non-CKD subjects. Results of multivariate regression models showed that with lower creatinine clearance 1 mL/min, DMF index was higher 0.02 teeth, and salivary flow rate lower 0.003 mL/min. CONCLUSIONS: There were no differences in dental status between patients with CKD and those without CKD, except that poor renal function is directly related with a higher DMFT index and lower salivary flow rate. Dental professionals should pay greater attention to oral problems during the progression of CKD to prevent deterioration of oral health.