| Literature DB >> 30582330 |
Josefa L López-Martínez1, Irene Torres-García1, Ignacio Rodríguez-García1, Manuel Muñoz-Dorado1, Miriam Álvarez-Corral1.
Abstract
CpTiCl2, prepared in situ by manganese reduction of CpTiCl3, is an excellent new system for the Barbier-type allylation and propargylation of carbonyl compounds. It can be used in catalytic amounts when combined with Et3N·HBr/TMSBr, which acts as a regenerating system. The high regio- and stereoselectivity shown by this system makes it useful for prenylation and crotylation processes in the synthesis of natural products.Entities:
Year: 2019 PMID： 30582330 DOI： 10.1021/acs.joc.8b02643
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354