Literature DB >> 30581010

Genetic mutations in linezolid-resistant Mycobacterium avium complex and Mycobacterium abscessus clinical isolates.

Su-Young Kim1, Byung Woo Jhun1, Seong Mi Moon1, Kyeongman Jeon1, O Jung Kwon1, Hee Jae Huh2, Nam Yong Lee2, Sung Jae Shin3, Charles L Daley4, Won-Jung Koh5.   

Abstract

There are no studies evaluating the mechanisms driving linezolid resistance in nontuberculous mycobacteria. The novel mutations G2599A and A2137T in the 23S rRNA gene and mutations A439G and G443A in the rplD gene associated with linezolid resistance were identified in linezolid-resistant M. avium complex isolates.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Drug resistance; Linezolid; Mycobacterium abscessus; Mycobacterium avium complex; Nontuberculous mycobacteria

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Year:  2018        PMID： 30581010     DOI： 10.1016/j.diagmicrobio.2018.10.022

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  2 in total

1.  Mycobacterium abscessus Associated Peritonitis with CAPD Successfully Treated Using a Linezolid and Tedizolid Containing Regimen Suggested Immunomodulatory Effects.

Authors:  Masafumi Seki; Yasuhiro Kamioka; Kazuki Takano; Haruka Imai; Mai Shoji; Maya Hariu; Yukari Kabutoya; Yuji Watanabe
Journal:  Am J Case Rep       Date:  2020-06-29

2.  In vitro Antimicrobial Activity Comparison of Linezolid, Tedizolid, Sutezolid and Delpazolid Against Slowly Growing Mycobacteria Isolated in Beijing, China.

Authors:  Xia Yu; Fengmin Huo; Fen Wang; Shu'an Wen; Guanglu Jiang; Yi Xue; Lingling Dong; Liping Zhao; Rui Zhu; Hairong Huang
Journal:  Infect Drug Resist       Date:  2021-11-09       Impact factor: 4.003
  2 in total

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