Literature DB >> 30580616

New bisbibenzyl and phenanthrene derivatives from Dendrobium scabrilingue and their α-glucosidase inhibitory activity.

Chalermporn Sarakulwattana1, Wanwimon Mekboonsonglarp2, Kittisak Likhitwitayawuid1, Pornchai Rojsitthisak3,4, Boonchoo Sritularak1,3.   

Abstract

Phytochemical investigation of the whole plant of Dendrobium scabrilingue resulted in the isolation of two new compounds namely dendroscabrols A (1) and B (2), along with eight known compounds (3-10). The structures of these compounds were determined by NMR and HR-ESI-MS experiments. All of the isolates were evaluated for their α-glucosidase inhibitory effect. Dendroscabrol B (2) and RF-3192C (10) showed the most potent α-glucosidase inhibitory activity. Dendroscabrol A (1), gigantol (5), coelonin (7) and lusianthridin (9) also exhibited strong activity as compared with the positive control acarbose.

Entities:  

Keywords:  Dendrobium scabrilingue; Orchidaceae; bisbibenzyl; phenanthrene; α-glucosidase

Year:  2018        PMID： 30580616     DOI： 10.1080/14786419.2018.1527839

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  5 in total

1.  Antioxidant Activities and Protective Effects of Dendropachol, a New Bisbibenzyl Compound from Dendrobium pachyglossum, on Hydrogen Peroxide-Induced Oxidative Stress in HaCaT Keratinocytes.

Authors:  Sakan Warinhomhoun; Chawanphat Muangnoi; Visarut Buranasudja; Wanwimon Mekboonsonglarp; Pornchai Rojsitthisak; Kittisak Likhitwitayawuid; Boonchoo Sritularak
Journal:  Antioxidants (Basel)       Date:  2021-02-06

2.  Four Novel Phenanthrene Derivatives with α-Glucosidase Inhibitory Activity from Gastrochilus bellinus.

Authors:  Htoo Tint San; Nutputsorn Chatsumpun; Thaweesak Juengwatanatrakul; Natapol Pornputtapong; Kittisak Likhitwitayawuid; Boonchoo Sritularak
Journal:  Molecules       Date:  2021-01-14       Impact factor: 4.411

3.  Secondary Metabolites in the Dendrobium heterocarpum Methanolic Extract and Their Impacts on Viability and Lipid Storage of 3T3-L1 Pre-Adipocytes.

Authors:  Sakan Warinhomhoun; Hnin Ei Ei Khine; Boonchoo Sritularak; Kittisak Likhitwitayawuid; Tomofumi Miyamoto; Chiaki Tanaka; Chuchard Punsawad; Yanyong Punpreuk; Rungroch Sungthong; Chatchai Chaotham
Journal:  Nutrients       Date:  2022-07-14       Impact factor: 6.706

4.  Genome-Wide Identification of Genes Related to Biosynthesis of Phenolic Acid Derivatives in Bletilla striata at Different Suspension Culture Stages.

Authors:  Houbo Liu; Ceyin Huang; Qingqing Li; Mufei Wang; Shiji Xiao; Junhua Shi; Yihuai He; Weie Wen; Lin Li; Delin Xu
Journal:  Front Plant Sci       Date:  2022-06-17       Impact factor: 6.627

5.  New Fluorene Derivatives from Dendrobium gibsonii and Their α-Glucosidase Inhibitory Activity.

Authors:  May Thazin Thant; Nutputsorn Chatsumpun; Wanwimon Mekboonsonglarp; Boonchoo Sritularak; Kittisak Likhitwitayawuid
Journal:  Molecules       Date:  2020-10-25       Impact factor: 4.411
  5 in total

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