Literature DB >> 30580320

What (or sometimes who) are organoids? And whose are they?

Andrea Lavazza.   

Abstract

In terms of ethical implications, Boers, van Delden and Bredenoord (2018) have made an interesting step forward with their model of organoids as hybrids, which seeks to find a balance between subject-like value and object-like value. Their framework aims to introduce effective procedures not to exploit donors and to increase their engagement, but it does not seem to take sufficient account of how organoids are used and how donors and society as a whole may want to act about such uses. I will concentrate my remarks on three points that I consider relevant. The first comment concerns the so-called mini-brains. The second one is related to the issue of consent and long-term 'control' over the organic material granted by donors. The last comment focuses on 'genetic minorities'. © Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  chimeras; clinical trials; donation/procurement of organs/tissues; neuroethics; stem cell research

Year:  2018        PMID: 30580320     DOI: 10.1136/medethics-2018-105268

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  5 in total

1.  Ethical Challenges in Organoid Use.

Authors:  Vasiliki Mollaki
Journal:  BioTech (Basel)       Date:  2021-06-28

Review 2.  Organoids: a systematic review of ethical issues.

Authors:  Dide de Jongh; Emma K Massey; Eline M Bunnik
Journal:  Stem Cell Res Ther       Date:  2022-07-23       Impact factor: 8.079

3.  Knowledge graphs of ethical concerns of cerebral organoids.

Authors:  Lulu Ding; Zhenyu Xiao; Xia Gong; Yaojin Peng
Journal:  Cell Prolif       Date:  2022-05-17       Impact factor: 8.755

4.  Moral Limits of Brain Organoid Research.

Authors:  Julian J Koplin; Julian Savulescu
Journal:  J Law Med Ethics       Date:  2019-12       Impact factor: 1.718

5.  Human cerebral organoids and consciousness: a double-edged sword.

Authors:  Andrea Lavazza
Journal:  Monash Bioeth Rev       Date:  2020-12
  5 in total

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