Literature DB >> 30580297

Pleuropulmonary tuberculosis with spinal lesions due to metastatic malignancy differentiated definitively on imaging.

Justine Gibson1,2, John Coucher3, Chris Coulter2,4, Geoffrey Eather1,2.   

Abstract

A healthy 31-year-old man presenting with back pain was found to have multiple spinal enhancing lesions on MRI. An incidental asymptomatic large pleural effusion was identified on investigations for the back pain and pleural and pulmonary tuberculosis (TB) was subsequently diagnosed. The radiographical features on MRI spine were not typical of spinal TB and a Ga68 DOTATATE Positron Emission Tomography (PET)/CT confirmed metastatic paraganglioma with multiple bone metastases. Although metastatic paraganglioma is rare, this case highlights that even in young patients dual pathology needs to be considered. Most importantly, it is a reminder to physicians managing TB of the clues that help distinguish spinal TB from important alternative causes, including metastatic malignancy. © BMJ Publishing Group Limited 2018. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  endocrine cancer; head and neck cancer; tuberculosis

Mesh:

Year:  2018        PMID: 30580297      PMCID: PMC6307567          DOI: 10.1136/bcr-2018-226160

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  10 in total

Review 1.  Imaging findings of Pott's disease.

Authors:  Antonio Rivas-Garcia; Silvana Sarria-Estrada; Carme Torrents-Odin; Lourdes Casas-Gomila; Elisa Franquet
Journal:  Eur Spine J       Date:  2012-06-09       Impact factor: 3.134

2.  Superiority of [68Ga]-DOTATATE PET/CT to Other Functional Imaging Modalities in the Localization of SDHB-Associated Metastatic Pheochromocytoma and Paraganglioma.

Authors:  Ingo Janssen; Elise M Blanchet; Karen Adams; Clara C Chen; Corina M Millo; Peter Herscovitch; David Taieb; Electron Kebebew; Hendrik Lehnert; Antonio T Fojo; Karel Pacak
Journal:  Clin Cancer Res       Date:  2015-04-14       Impact factor: 12.531

Review 3.  MR imaging assessment of the spine: infection or an imitation?

Authors:  Sung Hwan Hong; Ja-Young Choi; Joon Woo Lee; Na Ra Kim; Jung-Ah Choi; Heung Sik Kang
Journal:  Radiographics       Date:  2009 Mar-Apr       Impact factor: 5.333

Review 4.  Spinal tuberculosis: a review.

Authors:  Ravindra Kumar Garg; Dilip Singh Somvanshi
Journal:  J Spinal Cord Med       Date:  2011       Impact factor: 1.985

Review 5.  SDH-related pheochromocytoma and paraganglioma.

Authors:  Vitaly Kantorovich; Kathryn S King; Karel Pacak
Journal:  Best Pract Res Clin Endocrinol Metab       Date:  2010-06       Impact factor: 4.690

6.  Discrimination of tuberculous spondylitis from pyogenic spondylitis on MRI.

Authors:  Na-Young Jung; Won-Hee Jee; Kee-Yong Ha; Chun-Kun Park; Jae-Young Byun
Journal:  AJR Am J Roentgenol       Date:  2004-06       Impact factor: 3.959

7.  The role of 68Ga-DOTATATE PET/CT in suspected neuroendocrine tumors.

Authors:  Alexander R Haug; Ramona Cindea-Drimus; Christoph J Auernhammer; Martin Reincke; Björn Wängler; Christopher Uebleis; Gerwin P Schmidt; Burkhard Göke; Peter Bartenstein; Marcus Hacker
Journal:  J Nucl Med       Date:  2012-09-14       Impact factor: 10.057

Review 8.  Comparison of pyogenic spondylitis and tuberculous spondylitis.

Authors:  Kyu Yeol Lee
Journal:  Asian Spine J       Date:  2014-04-08

9.  (68)Ga-DOTATATE and (18)F-FDG PET/CT in Paraganglioma and Pheochromocytoma: utility, patterns and heterogeneity.

Authors:  Chian A Chang; David A Pattison; Richard W Tothill; Grace Kong; Tim J Akhurst; Rodney J Hicks; Michael S Hofman
Journal:  Cancer Imaging       Date:  2016-08-17       Impact factor: 3.909

10.  Missed Opportunities to Diagnose Tuberculosis Are Common Among Hospitalized Patients and Patients Seen in Emergency Departments.

Authors:  Aaron C Miller; Linnea A Polgreen; Joseph E Cavanaugh; Douglas B Hornick; Philip M Polgreen
Journal:  Open Forum Infect Dis       Date:  2015-12-19       Impact factor: 3.835

  10 in total

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