Bonnie Dorise1, Amit Trivedi2, Claire Galea3, Karen Walker4, Bhavesh Mehta2. 1. Grace Centre for Newborn Intensive Care, The Children's Hospital at Westmead, Sydney, NSW, Australia. Electronic address: bonnie.dorise@health.nsw.gov.au. 2. Grace Centre for Newborn Intensive Care, The Children's Hospital at Westmead, Sydney, NSW, Australia; University of Sydney, The Children's Hospital at Westmead Clinical School, Sydney, NSW, Australia. 3. Grace Centre for Newborn Intensive Care, The Children's Hospital at Westmead, Sydney, NSW, Australia; Cerebral Palsy Alliance, Sydney, NSW, Australia. 4. Grace Centre for Newborn Intensive Care, The Children's Hospital at Westmead, Sydney, NSW, Australia; University of Sydney, The Children's Hospital at Westmead Clinical School, Sydney, NSW, Australia; Cerebral Palsy Alliance, Sydney, NSW, Australia.
Abstract
OBJECTIVES: To assess the impact of feeding practices on growth in infants with Pierre Robin Sequence (PRS) during their inpatient stay in a neonatal intensive care unit in a large tertiary paediatric hospital setting. METHODS: A retrospective review of feeding practices in infants with PRS was conducted between January 2006 and September 2017. Baseline demographics, nutrition-related and general outcomes were collected. Feeding difficulties, length of stay (LOS) and malnutrition were the primary outcome measures. Feeding difficulties included absence or poor-quality suck, episodes of aspiration, use of proton pump inhibitors or multiple episodes of vomiting. Malnutrition was classified as a weight-for-age Z score of < -1. RESULTS: Analysis was conducted on 49 infants with PRS that met eligibility criteria. Feeding difficulties correlated with a longer LOS (24.1 vs 6.8 days (p = 0.001)) Z-scores differed significantly between birth and discharge (0.21(1.84) vs -1.27(2.14)) (p < 0.001*) with malnutrition being evident in 26 infants of which only 17 infants were seen by a dietitian. Presence of intrauterine growth restriction (IUGR) increased the likelihood of malnutrition (OR 1.40(CI-1.11-1.77)). CONCLUSION: Infants with PRS are highly likely to have feeding difficulties and malnutrition. Early intervention by a dietitian is recommended to reduce the impacts of feeding difficulties, meet elevated energy requirements and facilitate growth. Infants with a longer inpatient stay or presence of IUGR should have their growth and feeding routinely monitored. Crown
OBJECTIVES: To assess the impact of feeding practices on growth in infants with Pierre Robin Sequence (PRS) during their inpatient stay in a neonatal intensive care unit in a large tertiary paediatric hospital setting. METHODS: A retrospective review of feeding practices in infants with PRS was conducted between January 2006 and September 2017. Baseline demographics, nutrition-related and general outcomes were collected. Feeding difficulties, length of stay (LOS) and malnutrition were the primary outcome measures. Feeding difficulties included absence or poor-quality suck, episodes of aspiration, use of proton pump inhibitors or multiple episodes of vomiting. Malnutrition was classified as a weight-for-age Z score of < -1. RESULTS: Analysis was conducted on 49 infants with PRS that met eligibility criteria. Feeding difficulties correlated with a longer LOS (24.1 vs 6.8 days (p = 0.001)) Z-scores differed significantly between birth and discharge (0.21(1.84) vs -1.27(2.14)) (p < 0.001*) with malnutrition being evident in 26 infants of which only 17 infants were seen by a dietitian. Presence of intrauterine growth restriction (IUGR) increased the likelihood of malnutrition (OR 1.40(CI-1.11-1.77)). CONCLUSION:Infants with PRS are highly likely to have feeding difficulties and malnutrition. Early intervention by a dietitian is recommended to reduce the impacts of feeding difficulties, meet elevated energy requirements and facilitate growth. Infants with a longer inpatient stay or presence of IUGR should have their growth and feeding routinely monitored. Crown