| Literature DB >> 30578391 |
Ekkehard Grünig1,2, Christina Eichstaedt1,2, Joan-Albert Barberà3, Nicola Benjamin1, Isabel Blanco3, Eduardo Bossone4, Antonio Cittadini4, Gerry Coghlan5, Paul Corris6, Michele D'Alto7, Antonello D'Andrea7, Marion Delcroix8, Frances de Man9, Sean Gaine10, Stefano Ghio11, Simon Gibbs12, Lina Gumbiene13,14, Luke S Howard15, Martin Johnson16, Elena Jurevičienė13,14, David G Kiely17, Gabor Kovacs18,19, Alison MacKenzie16, Alberto M Marra20, Noel McCaffrey10, Paul McCaughey16, Robert Naeije21, Horst Olschewski18,19, Joanna Pepke-Zaba22, Abílio Reis23, Mário Santos23, Stéphanie Saxer24, Robert M Tulloh25, Silvia Ulrich24, Anton Vonk Noordegraaf9, Andrew J Peacock16.
Abstract
Objectives of this European Respiratory Society task force were to summarise current studies, to develop strategies for future research and to increase availability and awareness of exercise training for pulmonary hypertension (PH) patients.An evidence-based approach with clinical expertise of the task force members, based on both literature search and face-to-face meetings was conducted. The statement summarises current knowledge and open questions regarding clinical effects of exercise training in PH, training modalities, implementation strategies and pathophysiological mechanisms.In studies (784 PH patients in total, including six randomised controlled trials, three controlled trials, 10 prospective cohort studies and four meta-analyses), exercise training has been shown to improve exercise capacity, muscular function, quality of life and possibly right ventricular function and pulmonary haemodynamics. Nevertheless, further studies are needed to confirm these data, to investigate the impact on risk profiles and to identify the most advantageous training methodology and underlying pathophysiological mechanisms.As exercise training appears to be effective, cost-efficient and safe, but is scarcely reimbursed, support from healthcare institutions, commissioners of healthcare and research funding institutions is greatly needed. There is a strong need to establish specialised rehabilitation programmes for PH patients to enhance patient access to this treatment intervention.Entities:
Year: 2019 PMID: 30578391 DOI: 10.1183/13993003.00332-2018
Source DB: PubMed Journal: Eur Respir J ISSN: 0903-1936 Impact factor: 16.671