Bowen Hu1, Xi Yang1, Yujie Hu1, Qiunan Lyu1, Limin Liu1, Ce Zhu1, Chunguang Zhou1, Yueming Song2. 1. Department of Orthopedics Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China. 2. Department of Orthopedics Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China. Electronic address: sym_cd@163.com.
Abstract
OBJECTIVE: The nano-hydroxyapatite/polyamide66 (n-HA/PA66) cage is a novel biomimetic nonmetal cage, whereas the polyetheretherketone (PEEK) cage has been widely used for decades with excellent clinical outcomes. However, there has been no long-term comparison of these 2 cages in anterior cervical reconstruction. METHODS: This retrospective study included 98 patients who underwent single-level anterior cervical decompression and fusion (ACDF) from January 2009 to June 2011 with at least 7 years of follow-up; the PEEK cage was used in 51 patients (PEEK group), whereas the n-HA/PA66 cage was used in 47 (n-HA/PA66 group). The groups were compared regarding radiographic (cage subsidence, fusion status, cervical lordosis, and segmental sagittal alignment) and clinical (10-point visual analog scale and Japanese Orthopedic Association scores) parameters preoperatively, postoperatively, and at the final follow-up. RESULTS: The n-HA/PA66 and PEEK cages had similar fusion rates at the final follow-up (97.9% vs. 98.0%). The respective cage subsidence rates in the PEEK and n-HA/PA66 cage groups were 9.8% and 10.6%. There were no significant differences between the 2 groups in mean cervical lordosis, mean interbody height, segmental sagittal alignment, cervical lordosis, and 10-point visual analog scale and Japanese Orthopedic Association scores at the final follow-up. The n-HA/PA66 cages resulted in high fusion and low subsidence rates during long-term follow-up. CONCLUSIONS: After single-level ACDF, the n-HA/PA66 cage showed similar radiographic fusion, subsidence rate, and clinical results compared with the PEEK cage during 7 years of follow-up. These results suggest that the n-HA/PA66 cage could be comparable with the PEEK cage for ACDF.
OBJECTIVE: The nano-hydroxyapatite/polyamide66 (n-HA/PA66) cage is a novel biomimetic nonmetal cage, whereas the polyetheretherketone (PEEK) cage has been widely used for decades with excellent clinical outcomes. However, there has been no long-term comparison of these 2 cages in anterior cervical reconstruction. METHODS: This retrospective study included 98 patients who underwent single-level anterior cervical decompression and fusion (ACDF) from January 2009 to June 2011 with at least 7 years of follow-up; the PEEK cage was used in 51 patients (PEEK group), whereas the n-HA/PA66 cage was used in 47 (n-HA/PA66 group). The groups were compared regarding radiographic (cage subsidence, fusion status, cervical lordosis, and segmental sagittal alignment) and clinical (10-point visual analog scale and Japanese Orthopedic Association scores) parameters preoperatively, postoperatively, and at the final follow-up. RESULTS: The n-HA/PA66 and PEEK cages had similar fusion rates at the final follow-up (97.9% vs. 98.0%). The respective cage subsidence rates in the PEEK and n-HA/PA66 cage groups were 9.8% and 10.6%. There were no significant differences between the 2 groups in mean cervical lordosis, mean interbody height, segmental sagittal alignment, cervical lordosis, and 10-point visual analog scale and Japanese Orthopedic Association scores at the final follow-up. The n-HA/PA66 cages resulted in high fusion and low subsidence rates during long-term follow-up. CONCLUSIONS: After single-level ACDF, the n-HA/PA66 cage showed similar radiographic fusion, subsidence rate, and clinical results compared with the PEEK cage during 7 years of follow-up. These results suggest that the n-HA/PA66 cage could be comparable with the PEEK cage for ACDF.
Authors: Jakub Litak; Wojciech Czyzewski; Michał Szymoniuk; Bartlomiej Pastuszak; Joanna Litak; Grzegorz Litak; Cezary Grochowski; Mansur Rahnama-Hezavah; Piotr Kamieniak Journal: Materials (Basel) Date: 2022-04-15 Impact factor: 3.748