Literature DB >> 30576660

A BAF'ling Approach to Curing HIV.

Sakshi Tomar1, Ibraheem Ali1, Melanie Ott2.   

Abstract

Latency is the primary barrier to the development of a long-sought cure for HIV-1. In this issue of Cell Chemical Biology, Marian et al., (2018) describe the development of novel compounds targeting the BAF chromatin remodeling complex to reverse HIV latency, with the potential to provide a functional cure.
Copyright © 2018 Elsevier Ltd. All rights reserved.

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Year:  2018        PMID： 30576660      PMCID： PMC6582950          DOI： 10.1016/j.chembiol.2018.12.007

Source DB:  PubMed          Journal:  Cell Chem Biol        ISSN： 2451-9448            Impact factor:   8.116


  10 in total

Review 1.  Epigenetic regulation of HIV latency.

Authors:  Shweta Hakre; Leonard Chavez; Kotaro Shirakawa; Eric Verdin
Journal:  Curr Opin HIV AIDS       Date:  2011-01       Impact factor: 4.283

2.  The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter.

Authors:  Tokameh Mahmoudi; Maribel Parra; Robert G J Vries; Steven E Kauder; C Peter Verrijzer; Melanie Ott; Eric Verdin
Journal:  J Biol Chem       Date:  2006-05-10       Impact factor: 5.157

3.  Small Molecule Targeting of Specific BAF (mSWI/SNF) Complexes for HIV Latency Reversal.

Authors:  Christine A Marian; Mateusz Stoszko; Lili Wang; Matthew W Leighty; Elisa de Crignis; Chad A Maschinot; Jovylyn Gatchalian; Benjamin C Carter; Basudev Chowdhury; Diana C Hargreaves; Jeremy R Duvall; Gerald R Crabtree; Tokameh Mahmoudi; Emily C Dykhuizen
Journal:  Cell Chem Biol       Date:  2018-09-06       Impact factor: 8.116

4.  The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin-Remodeling Complexes.

Authors:  Ryan J Conrad; Parinaz Fozouni; Sean Thomas; Hendrik Sy; Qiang Zhang; Ming-Ming Zhou; Melanie Ott
Journal:  Mol Cell       Date:  2017-08-24       Impact factor: 17.970

Review 5.  Getting the "Kill" into "Shock and Kill": Strategies to Eliminate Latent HIV.

Authors:  Youry Kim; Jenny L Anderson; Sharon R Lewin
Journal:  Cell Host Microbe       Date:  2018-01-10       Impact factor: 21.023

6.  VP16-dependent association of chromatin-modifying coactivators and underrepresentation of histones at immediate-early gene promoters during herpes simplex virus infection.

Authors:  Francisco J Herrera; Steven J Triezenberg
Journal:  J Virol       Date:  2004-09       Impact factor: 5.103

7.  Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation.

Authors:  C Van Lint; S Emiliani; M Ott; E Verdin
Journal:  EMBO J       Date:  1996-03-01       Impact factor: 11.598

Review 8.  ATP-dependent chromatin remodeling complexes as novel targets for cancer therapy.

Authors:  Kimberly Mayes; Zhijun Qiu; Aiman Alhazmi; Joseph W Landry
Journal:  Adv Cancer Res       Date:  2014       Impact factor: 6.242

9.  Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency.

Authors:  Haleh Rafati; Maribel Parra; Shweta Hakre; Yuri Moshkin; Eric Verdin; Tokameh Mahmoudi
Journal:  PLoS Biol       Date:  2011-11-29       Impact factor: 8.029

10.  Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation.

Authors:  E Verdin; P Paras; C Van Lint
Journal:  EMBO J       Date:  1993-08       Impact factor: 11.598
  10 in total
  3 in total

Review 1.  Targeting HIV-1 proviral transcription.

Authors:  Alex Olson; Binita Basukala; Wilson W Wong; Andrew J Henderson
Journal:  Curr Opin Virol       Date:  2019-08-29       Impact factor: 7.121

2.  Tat inhibition by didehydro-Cortistatin A promotes heterochromatin formation at the HIV-1 long terminal repeat.

Authors:  Chuan Li; Guillaume Mousseau; Susana T Valente
Journal:  Epigenetics Chromatin       Date:  2019-04-16       Impact factor: 4.954

Review 3.  Forging a Functional Cure for HIV: Transcription Regulators and Inhibitors.

Authors:  Sonia Mediouni; Shuang Lyu; Susan M Schader; Susana T Valente
Journal:  Viruses       Date:  2022-09-07       Impact factor: 5.818
  3 in total

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