Pasquale Maffia1,2,3, Alberto Mantovani4,5,6, Michael Spedding7. 1. Centre for Immunobiology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK. 2. Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK. 3. Department of Pharmacy, University of Naples Federico II, Naples, Italy. 4. Humanitas Clinical and Research Center, via Manzoni 56, Rozzano, Milan, Italy. 5. Humanitas University, via Rita Levi Montalcini, Pieve Emanuele, Milan, Italy. 6. The William Harvey Research Institute, Queen Mary University of London, London, UK. 7. Spedding Research Solutions SAS, 6 Rue Ampere, Le Vesinet, France.