Literature DB >> 30575975

Gender difference in clinical conditions among hospitalized adults with myotonic dystrophy.

Lijing Ouyang1, Yinding Wang1, Rodolfo Valdez1, Nicholas Johnson2, Laurie Gutmann3, Natalie Street1, Julie Bolen1.   

Abstract

INTRODUCTION: In this study we examined gender differences in adult hospitalizations with myotonic dystrophy (DM).
METHODS: From the Nationwide Inpatient Sample (NIS) 2010-2014, we identified 1,891 adult hospitalizations with a DM diagnosis and constructed a comparison group of hospitalizations without DM using propensity score matching. We calculated relative risk by gender for 44 clinical diagnoses that each accounted for at least 5% of DM hospitalizations.
RESULTS: Hospitalizations with DM were longer (4.8 vs. 4.1 days, P < 0.0001) and more costly ($13,241 vs. $11,458, P < 0.0001) than those without DM. More than half (25 of 44) of the conditions co-occurring with DM hospitalizations did not differ in their relative risks by gender. For those that differed by gender, only 5 were specific to DM, compared with hospitalizations without DM. DISCUSSION: Our findings highlight the importance of comprehensive and coordinated care for DM rather than gender-oriented care in the inpatient setting. Muscle Nerve 59:348-353, 2019.
© 2018 Wiley Periodicals, Inc.

Entities:  

Keywords:  DM; co-occurring conditions; gender differences; hospitalizations; matching

Mesh:

Year:  2019        PMID: 30575975      PMCID: PMC7702279          DOI: 10.1002/mus.26402

Source DB:  PubMed          Journal:  Muscle Nerve        ISSN: 0148-639X            Impact factor:   3.217


  8 in total

1.  Assessing the influence of age and gender on the phenotype of myotonic dystrophy type 2.

Authors:  Federica Montagnese; Stefania Mondello; Stephan Wenninger; Wolfram Kress; Benedikt Schoser
Journal:  J Neurol       Date:  2017-10-30       Impact factor: 4.849

2.  Relative risks for comorbidities associated with myotonic dystrophy: A population-based analysis.

Authors:  Nicholas E Johnson; Diana Abbott; Lisa A Cannon-Albright
Journal:  Muscle Nerve       Date:  2015-08-26       Impact factor: 3.217

3.  Correlates of tumor development in patients with myotonic dystrophy.

Authors:  Maya Das; Richard T Moxley; James E Hilbert; William B Martens; Lisa Letren; Mark H Greene; Shahinaz M Gadalla
Journal:  J Neurol       Date:  2012-05-23       Impact factor: 4.849

Review 4.  A Systematic Review and Meta-analysis on the Epidemiology of the Muscular Dystrophies.

Authors:  Jean K Mah; Lawrence Korngut; Kirsten M Fiest; Jonathan Dykeman; Lundy J Day; Tamara Pringsheim; Nathalie Jette
Journal:  Can J Neurol Sci       Date:  2016-01       Impact factor: 2.104

5.  Cancer risk in DM1 is sex-related and linked to miRNA-200/141 downregulation.

Authors:  Roberto Fernández-Torrón; Mikel García-Puga; José-Ignacio Emparanza; Miren Maneiro; Ana-María Cobo; Juan-José Poza; Juan-Bautista Espinal; Miren Zulaica; Irune Ruiz; Loreto Martorell; David Otaegui; Ander Matheu; Adolfo López de Munain
Journal:  Neurology       Date:  2016-08-24       Impact factor: 9.910

Review 6.  Myotonic Dystrophy Type 1 Management and Therapeutics.

Authors:  Cheryl A Smith; Laurie Gutmann
Journal:  Curr Treat Options Neurol       Date:  2016-12       Impact factor: 3.598

7.  High frequency of gastrointestinal manifestations in myotonic dystrophy type 1 and type 2.

Authors:  James E Hilbert; Richard J Barohn; Paula R Clemens; Elizabeth A Luebbe; William B Martens; Michael P McDermott; Amy L Parkhill; Rabi Tawil; Charles A Thornton; Richard T Moxley
Journal:  Neurology       Date:  2017-08-30       Impact factor: 9.910

8.  Gender as a Modifying Factor Influencing Myotonic Dystrophy Type 1 Phenotype Severity and Mortality: A Nationwide Multiple Databases Cross-Sectional Observational Study.

Authors:  Celine Dogan; Marie De Antonio; Dalil Hamroun; Hugo Varet; Marianne Fabbro; Felix Rougier; Khadija Amarof; Marie-Christine Arne Bes; Anne-Laure Bedat-Millet; Anthony Behin; Remi Bellance; Françoise Bouhour; Celia Boutte; François Boyer; Emmanuelle Campana-Salort; Françoise Chapon; Pascal Cintas; Claude Desnuelle; Romain Deschamps; Valerie Drouin-Garraud; Xavier Ferrer; Helene Gervais-Bernard; Karima Ghorab; Pascal Laforet; Armelle Magot; Laurent Magy; Dominique Menard; Marie-Christine Minot; Aleksandra Nadaj-Pakleza; Sybille Pellieux; Yann Pereon; Marguerite Preudhomme; Jean Pouget; Sabrina Sacconi; Guilhem Sole; Tanya Stojkovich; Vincent Tiffreau; Andoni Urtizberea; Christophe Vial; Fabien Zagnoli; Gilbert Caranhac; Claude Bourlier; Gerard Riviere; Alain Geille; Romain K Gherardi; Bruno Eymard; Jack Puymirat; Sandrine Katsahian; Guillaume Bassez
Journal:  PLoS One       Date:  2016-02-05       Impact factor: 3.240

  8 in total

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