BACKGROUND AND AIMS: Functional gastrointestinal disorders are prevalent worldwide and alterations of gut-brain axis and intestinal barrier integrity may play a pivotal role in both the pathophysiology and clinical course of these bowel malfunctions. We aimed to assess the prevalence of abdominal pain in a selected adult population of Poland to determine potential environmental factors associated with gastrointestinal complaints. METHODS: There were 1479 individuals - 657 women (44.42%) and 822 men (55.58%), aged 24.20±6.08 years. The responders fulfilled an authors' questionnaire based on Rome II and III criteria focused on the abdominal pain prevalence and environmental factors involved in its occurrence. RESULTS: The frequency of abdominal pain was found to be as high as 19.2%. Male gender (n=822) and basic education level (n=151) lowered the risk of abdominal pain occurrence (OR=0.7, p<0.012 and OR=0.5, p<0.021, respectively). Psychological distress, proton pump inhibitors (PPIs) and antibiotics usage were found as risk factors of abdominal pain (OR=2.503, p<0.01; OR=3.308, p<0.01; OR=3.105, p<0.01, respectively). CONCLUSIONS: Abdominal pain is prevalent in young adult inhabitants of Poland, especially in women. Intense psychological stress, as well as PPIs and antibiotics usage elevate the risk.
BACKGROUND AND AIMS: Functional gastrointestinal disorders are prevalent worldwide and alterations of gut-brain axis and intestinal barrier integrity may play a pivotal role in both the pathophysiology and clinical course of these bowel malfunctions. We aimed to assess the prevalence of abdominal pain in a selected adult population of Poland to determine potential environmental factors associated with gastrointestinal complaints. METHODS: There were 1479 individuals - 657 women (44.42%) and 822 men (55.58%), aged 24.20±6.08 years. The responders fulfilled an authors' questionnaire based on Rome II and III criteria focused on the abdominal pain prevalence and environmental factors involved in its occurrence. RESULTS: The frequency of abdominal pain was found to be as high as 19.2%. Male gender (n=822) and basic education level (n=151) lowered the risk of abdominal pain occurrence (OR=0.7, p<0.012 and OR=0.5, p<0.021, respectively). Psychological distress, proton pump inhibitors (PPIs) and antibiotics usage were found as risk factors of abdominal pain (OR=2.503, p<0.01; OR=3.308, p<0.01; OR=3.105, p<0.01, respectively). CONCLUSIONS:Abdominal pain is prevalent in young adult inhabitants of Poland, especially in women. Intense psychological stress, as well as PPIs and antibiotics usage elevate the risk.
Authors: Zlatan Mujagic; Melpomeni Kasapi; Daisy Mae Jonkers; Isabel Garcia-Perez; Lisa Vork; Zsa Zsa R M Weerts; Jose Ivan Serrano-Contreras; Alexandra Zhernakova; Alexander Kurilshikov; Jamie Scotcher; Elaine Holmes; Cisca Wijmenga; Daniel Keszthelyi; Jeremy K Nicholson; Joram M Posma; Ad Am Masclee Journal: Gut Microbes Date: 2022 Jan-Dec
Authors: Mikołaj Kamiński; Michał Borger; Piotr Prymas; Agnieszka Muth; Adam Stachowski; Igor Łoniewski; Wojciech Marlicz Journal: Int J Environ Res Public Health Date: 2020-02-06 Impact factor: 3.390