Literature DB >> 30572106

Victims of chemical terrorism, a family of four who were exposed to sulfur mustard.

S Sezigen1, K Ivelik2, M Ortatatli3, M Almacioglu4, M Demirkasimoglu5, R K Eyison3, Z I Kunak3, L Kenar3.   

Abstract

Sulfur mustard (SM) was responsible for more than 80% of all documented chemical casualties during the Great War. Recent literature on clinic picture of SM exposure remained so limited with the sporadic cases who were accidentally exposed to SM especially either in Western Europe or China. We reported a Syrian family of four who became victims of chemical terrorism due to SM exposure and we described the detailed clinical course of the family including the medical history, initial symptomatology, clinical examination, hematological data, and initial treatment in the first 48 hours after exposure at Kilis State Hospital, Turkey. The principles of our therapeutic approaches were designed according to the total affected body surface area, severity of cutaneous and respiratory lesions, and existing hematological disorders. SM is still considered as a critical vesicant agent and a current threat because of its ease of synthesis. Chemical terrorist attacks of non-state actors or terrorist organizations with "home-made" SM is likely such a threat which is targeting health systems of developed and developing countries. Except sarin attacks in Japan, the literature depends on real incidents of chemical terrorism is so rare and for this reason we have gaps and challanges in the prepardness of medical response system against chemical terrorism. Medical management could be performed adequetly only if the response system is well planned, well equipped, and well prepared for overburdened medical facilities filled with SM contaminated casualties after a chemical terrorist attack.
Copyright © 2018 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  CBRN; Chemical casualties; Chemical terrorism; Decontamination; Mustard gas; Sulfur mustard

Mesh:

Substances:

Year:  2018        PMID: 30572106     DOI: 10.1016/j.toxlet.2018.12.006

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN: 0378-4274            Impact factor:   4.372


  6 in total

Review 1.  Interpol review of toxicology 2016-2019.

Authors:  Wing-Sum Chan; George Fai Wong; Chi-Wai Hung; Yau-Nga Wong; Kit-Mai Fung; Wai-Kit Lee; Kwok-Leung Dao; Chung-Wing Leung; Kam-Moon Lo; Wing-Man Lee; Bobbie Kwok-Keung Cheung
Journal:  Forensic Sci Int       Date:  2020-05-23       Impact factor: 2.395

2.  Small-interfering RNA for c-Jun attenuates cell death by preventing JNK-dependent PARP1 cleavage and DNA fragmentation in nitrogen mustard-injured immortalized human bronchial epithelial cells.

Authors:  Feng Ye; Guorong Dan; Yuanpeng Zhao; Wenpei Yu; Jin Cheng; Mingliang Chen; Yan Sai; Zhongmin Zou
Journal:  Toxicol Res (Camb)       Date:  2021-08-31       Impact factor: 2.680

3.  Health perspectives among Halabja's civilian survivors of sulfur mustard exposure with respiratory symptoms-A qualitative study.

Authors:  Faraidoun Moradi; Mia Söderberg; Fazil Moradi; Bledar Daka; Anna-Carin Olin; Mona Lärstad
Journal:  PLoS One       Date:  2019-06-21       Impact factor: 3.240

4.  Chronic senescent human mesenchymal stem cells as possible contributor to the wound healing disorder after exposure to the alkylating agent sulfur mustard.

Authors:  Simone Rothmiller; Niklas Jäger; Nicole Meier; Thimo Meyer; Adrian Neu; Dirk Steinritz; Horst Thiermann; Michael Scherer; Christoph Rummel; Aswin Mangerich; Alexander Bürkle; Annette Schmidt
Journal:  Arch Toxicol       Date:  2021-01-25       Impact factor: 5.153

5.  Modeling and Risk Analysis of Chemical Terrorist Attacks: A Bayesian Network Method.

Authors:  Rongchen Zhu; Xiaofeng Hu; Xin Li; Han Ye; Nan Jia
Journal:  Int J Environ Res Public Health       Date:  2020-03-19       Impact factor: 3.390

Review 6.  N-Acetylcysteine as a treatment for sulphur mustard poisoning.

Authors:  Thomas W Sawyer
Journal:  Free Radic Biol Med       Date:  2020-09-25       Impact factor: 7.376

  6 in total

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