| Literature DB >> 30571720 |
Anne-Sofie Helvik, Geir Selbæk, Jūratė Šaltytė Benth, Irene Røen, Sverre Bergh.
Abstract
[This corrects the article DOI: 10.1371/journal.pone.0206147.].Entities:
Year: 2018 PMID: 30571720 PMCID: PMC6301691 DOI: 10.1371/journal.pone.0209875
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Prevalence, incidence and persistence of significant neuropsychiatric symptoms (NPS) at each assessment (%).
| T1 (Baseline) | T2 (6 months) | T3 (12 months) | T4 (18 months) | T5 (24 months) | T6 (30 months) | |
|---|---|---|---|---|---|---|
| Prevalence | ||||||
| Delusions | 16.0 | 18.5 | 19.9 | 22.3 | 22.5 | 21.7 |
| Hallucinations | 5.8 | 8.2 | 5.0 | 8.7 | 10.4 | 7.6 |
| Agitation | 16.2 | 16.0 | 21.6 | 22.3 | 27.1 | 25.1 |
| Depression | 21.8 | 22.0 | 21.6 | 23.2 | 21.3 | 21.6 |
| Anxiety | 21.9 | 20.8 | 21.2 | 24.9 | 26.5 | 24.1 |
| Euphoria | 3.7 | 4.2 | 4.6 | 5.3 | 6.4 | 5.9 |
| Apathy | 16.6 | 12.2 | 13.5 | 17.5 | 23.4 | 21.9 |
| Disinhibition | 16.1 | 16.6 | 18.5 | 19.0 | 29.2 | 26.6 |
| Irritability | 19.2 | 24.8 | 27.3 | 34.5 | 36.8 | 37.1 |
| Aberrant Motor Behavior | 12.0 | 11.4 | 12.1 | 14.4 | 15.1 | 14.0 |
| Nighttime Behavior | 17.0 | 15.0 | 11.8 | 12.0 | 13.9 | 10.3 |
| Appetite and eating disorder | 10.1 | 9.5 | 7.4 | 14.1 | 12.3 | 12.3 |
| Any symptom | 61.9 | 55.5 | 59.5 | 67.0 | 69.6 | 65.4 |
| Cumulative incidence (%) and incidence between two consecutive time points | ||||||
| Cumulative incidence (N = 583) | T1-T2 | T2-T3 | T3-T4 | T4-T5 | T5-T6 | |
| Delusions | 24.5 | 13.2 | 9.5 | 11.5 | 12.6 | 11.4 |
| Hallucinations | 10.8 | 5.8 | 2.0 | 4.5 | 3.7 | 2.4 |
| Agitation | 23.7 | 9.7 | 12.6 | 12.4 | 12.6 | 10.5 |
| Depression | 22.7 | 14.4 | 12.3 | 14.0 | 9.8 | 9.7 |
| Anxiety | 24.7 | 12.4 | 12.3 | 13.9 | 11.9 | 13.1 |
| Euphoria | 9.1 | 3.2 | 2.8 | 4.0 | 4.9 | 3.4 |
| Apathy | 25.5 | 7.8 | 10.4 | 12.1 | 15.7 | 9.7 |
| Disinhibition | 24.7 | 9.0 | 10.4 | 11.4 | 18.0 | 13.5 |
| Irritability | 31.6 | 15.0 | 13.6 | 22.0 | 15.0 | 21.0 |
| Aberrant Motor Behavior | 17.4 | 6.7 | 6.1 | 9.2 | 10.0 | 7.5 |
| Nighttime Behavior | 15.8 | 7.9 | 4.5 | 6.4 | 8.1 | 4.3 |
| Appetite and eating disorder | 23.6 | 8.9 | 5.8 | 12.4 | 8.3 | 7.6 |
| Any symptom | 28.7 | 33.7 | 33.7 | 47.9 | 36.5 | 24.1 |
| Persistence of symptoms at two consecutive time points (%) | ||||||
| T1-T2 | T2-T3 | T3-T4 | T4-T5 | T5-T6 | ||
| Delusions | 46.4 | 66.7 | 62.1 | 52.7 | 54.3 | |
| Hallucinations | 48.0 | 48.0 | 66.7 | 75.0 | 55.6 | |
| Agitation | 52.3 | 72.5 | 57.6 | 70.7 | 63.6 | |
| Depression | 52.3 | 59.4 | 57.4 | 58.8 | 58.1 | |
| Anxiety | 52.7 | 58.8 | 61.7 | 67.7 | 61.7 | |
| Euphoria | 27.8 | 31.3 | 33.3 | 35.7 | 54.5 | |
| Apathy | 35.9 | 42.9 | 52.5 | 51.2 | 56.5 | |
| Disinhibition | 53.7 | 58.2 | 56.9 | 63.3 | 63.0 | |
| Irritability | 64.1 | 71.6 | 67.5 | 73.6 | 71.6 | |
| Aberrant Motor Behavior | 43.4 | 57.1 | 56.3 | 38.9 | 50.0 | |
| Nighttime Behavior | 51.4 | 50.0 | 45.9 | 64.0 | 44.8 | |
| Appetite and eating disorder | 17.1 | 40.0 | 31.8 | 39.4 | 45.0 | |
| Any symptom | 70.1 | 82.1 | 80.2 | 86.3 | 84.1 | |