| Literature DB >> 30570750 |
Xinggang Wang1, Junbo Ge1, Ruizhen Chen1.
Abstract
Latency associated peptide (LAP) is a protein expressed on the membrane of some regulatory T cells (Treg). LAP+ Treg have a greater immunomodulatory effect than that of their negative counterparts. In this study, we presented the data on the proportion of LAP+ Treg out of CD4+ cells in mice with viral myocarditis, which we believed was more sensitive and specific than that of the ratio of total Treg in CD4+ cells. Comparing with the previously recognized total Treg, LAP+ Treg was a better biomarker on myocardial inflammation.Entities:
Keywords: inflammation; latency associated peptide (LAP+) regulatory T cells (Treg); viral myocarditis
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Year: 2019 PMID： 30570750 DOI： 10.1002/jmv.25378
Source DB: PubMed Journal: J Med Virol ISSN： 0146-6615 Impact factor: 2.327