Literature DB >> 30568975

Validation of an Antimicrobial Stewardship-Driven Verigene Blood-Culture Gram-Negative Treatment Algorithm to Improve Appropriateness of Antibiotics.

Kimberly C Claeys1, K E Schlaffer2, E L Heil1, S Leekha3, J K Johnson4.   

Abstract

Rapid diagnostic testing (RDT) allows for early adjustment of antibiotic therapy. This study examined the potential impact of a stewardship-driven antibiotic treatment algorithm, incorporating RDT into the management of Gram-negative bacteremia. The proposed algorithm would have resulted in 88.4% of cases receiving appropriate antibiotic therapy versus 78.1% by standard of care (P = .014).

Entities:  

Keywords:  diagnostic stewardship; multiplex PCR; rapid diagnostic

Year:  2018        PMID： 30568975      PMCID： PMC6194422          DOI： 10.1093/ofid/ofy233

Source DB:  PubMed          Journal:  Open Forum Infect Dis        ISSN： 2328-8957            Impact factor:   3.835


  8 in total

1.  Impact of a Rapid Blood Culture Diagnostic Test in a Children's Hospital Depends on Gram-Positive versus Gram-Negative Organism and Day versus Night Shift.

Authors:  Lillian J Juttukonda; Sophie Katz; Jessica Gillon; Jonathon Schmitz; Ritu Banerjee
Journal:  J Clin Microbiol       Date:  2020-03-25       Impact factor: 5.948

2.  Impact of Pharmacist Involvement on the Utility of a Gram-Negative Blood Culture Identification Panel on Antimicrobial Usage.

Authors:  Caitlin Bowman; Melissa Holloway; Lisa Scott; Carmen Russell; Sonia Lott; Raid Amin
Journal:  J Pharm Technol       Date:  2021-09-18

3.  Management of Gram-Negative Bloodstream Infections in the Era of Rapid Diagnostic Testing: Impact With and Without Antibiotic Stewardship.

Authors:  Kimberly C Claeys; Emily L Heil; Stephanie Hitchcock; J Kristie Johnson; Surbhi Leekha
Journal:  Open Forum Infect Dis       Date:  2020-09-12       Impact factor: 3.835

4.  An antibiotic stewardship program in a surgical ICU of a resource-limited country: financial impact with improved clinical outcomes.

Authors:  Kashif Hussain; Muhammad Faisal Khan; Gul Ambreen; Syed Shamim Raza; Seema Irfan; Kiren Habib; Hasnain Zafar
Journal:  J Pharm Policy Pract       Date:  2020-10-06

5.  Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP).

Authors:  Alexis Tabah; Matteo Bassetti; Marin H Kollef; Jean-Ralph Zahar; José-Artur Paiva; Jean-Francois Timsit; Jason A Roberts; Jeroen Schouten; Helen Giamarellou; Jordi Rello; Jan De Waele; Andrew F Shorr; Marc Leone; Garyphallia Poulakou; Pieter Depuydt; Jose Garnacho-Montero
Journal:  Intensive Care Med       Date:  2019-11-28       Impact factor: 17.440

6.  A Baker's Dozen of Top Antimicrobial Stewardship Intervention Publications in 2018.

Authors:  Elias B Chahine; Spencer H Durham; Krutika N Mediwala; Daniel B Chastain; Timothy P Gauthier; Brandon K Hill; Bruce M Jones; Jamie J Kisgen; Ashley H Marx; Kayla R Stover; Marylee V Worley; Christopher M Bland; P Brandon Bookstaver
Journal:  Open Forum Infect Dis       Date:  2019-10-15       Impact factor: 3.835

7.  Performance of the eazyplex® BloodScreen GN as a simple and rapid molecular test for identification of Gram-negative bacteria from positive blood cultures.

Authors:  Katharina Bach; Birgit Edel; Steffen Höring; Lucie Bartoničkova; Stefan Glöckner; Bettina Löffler; Christina Bahrs; Jürgen Rödel
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2021-11-22       Impact factor: 3.267

Review 8.  Diagnosis and Management of Bloodstream Infections With Rapid, Multiplexed Molecular Assays.

Authors:  Sherry A Dunbar; Christopher Gardner; Shubhagata Das
Journal:  Front Cell Infect Microbiol       Date:  2022-03-16       Impact factor: 5.293
  8 in total

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