Literature DB >> 30568565

From Medical Prescription to Patient Compliance: A Qualitative Insight into the Neurologist-Patient Relationship in Multiple Sclerosis.

Vincent Schlegel, Emmanuelle Leray.   

Abstract

BACKGROUND: Approximately 12 disease-modifying treatments are available worldwide for patients with relapsing multiple sclerosis (MS). These recent therapeutic advances have led to major changes in patient and neurologist attitudes toward drug prescription. Herein, we aimed to characterize patient choice regarding treatment for MS and identify how neurologists assess and monitor patient compliance during follow-up.
METHODS: In 29 patients with MS, we observed visits to their neurologist to understand how questions related to compliance were addressed in the doctor-patient relationship. Face-to-face interviews were conducted with 15 of the 29 patients to discuss how they dealt with their drug prescription from a patient-centered perspective.
RESULTS: Of the 15 patients with MS, nine were offered a choice of treatment. However, we found that neurologists were not always willing to consider the patients' input. Even if physicians attempt to align treatment choice with patient preferences to ensure compliance, preferences are often assumed rather than solicited from patients. Furthermore, patients may be unwilling to make their own treatment decisions. Various ways for neurologists to assess compliance during visits were also identified. Noncompliance can be considered as a way for patients to communicate their preferences and demonstrate involvement in their drug therapy, and it can lead to a renegotiation of the current treatment course.
CONCLUSIONS: These findings suggest that the neurologist-patient relationship has a great influence on patient compliance throughout the MS disease course.

Entities:  

Keywords:  Compliance; Doctor-patient relationship; Multiple Sclerosis; Neurologist; Noncompliance; Patient preference; Qualitative analysis

Year:  2018        PMID: 30568565      PMCID: PMC6295879          DOI: 10.7224/1537-2073.2017-043

Source DB:  PubMed          Journal:  Int J MS Care        ISSN: 1537-2073


  15 in total

1.  Religious attitudes toward prescriptions, medicines, and doctors in France.

Authors:  Sylvie Fainzang
Journal:  Cult Med Psychiatry       Date:  2005-12

2.  On practices of 'good doctoring': reconsidering the relationship between provider roles and patient adherence.

Authors:  Karen Lutfey
Journal:  Sociol Health Illn       Date:  2005-05

Review 3.  Multiple sclerosis: current and emerging disease-modifying therapies and treatment strategies.

Authors:  Dean M Wingerchuk; Jonathan L Carter
Journal:  Mayo Clin Proc       Date:  2014-02       Impact factor: 7.616

4.  Patient compliance--whose responsibility?

Authors:  F M Ross
Journal:  Soc Sci Med       Date:  1991       Impact factor: 4.634

5.  Patient non-compliance: deviance or reasoned decision-making?

Authors:  J L Donovan; D R Blake
Journal:  Soc Sci Med       Date:  1992-03       Impact factor: 4.634

Review 6.  Discourse on safe drug use: symbolic logics and ethical aspects.

Authors:  Sylvie Fainzang
Journal:  Drug Saf       Date:  2010-08-01       Impact factor: 5.606

Review 7.  Narrative review of the literature on adherence to disease-modifying therapies among patients with multiple sclerosis.

Authors:  Joseph Menzin; Christina Caon; Christine Nichols; Leigh Ann White; Mark Friedman; Michael W Pill
Journal:  J Manag Care Pharm       Date:  2013 Jan-Feb

8.  From compliance to concordance: barriers to accomplishing a re-framed model of health care interactions.

Authors:  Paul Bissell; Carl R May; Peter R Noyce
Journal:  Soc Sci Med       Date:  2004-02       Impact factor: 4.634

Review 9.  Fostering adherence to injectable disease-modifying therapies in multiple sclerosis.

Authors:  Alessandra Lugaresi; Maria Rosa Rottoli; Francesco Patti
Journal:  Expert Rev Neurother       Date:  2014-08-11       Impact factor: 4.618

10.  Patient perceptions of multiple sclerosis and its treatment.

Authors:  Jérôme de Seze; Florent Borgel; Frédérique Brudon
Journal:  Patient Prefer Adherence       Date:  2012-04-04       Impact factor: 2.711

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  5 in total

1.  Effect of Health Care Providers' Focused Discussion and Proactive Education About Relapse Management on Patient Reporting of Multiple Sclerosis Relapse.

Authors:  Royce W Waltrip; Nancy Mahler; Alina Ahsan; Leslie B Herbert
Journal:  Int J MS Care       Date:  2021-02-08

Review 2.  A Targeted Literature Search and Phenomenological Review of Perspectives of People with Multiple Sclerosis and Healthcare Professionals of the Immunology of Disease-Modifying Therapies.

Authors:  Jeri Burtchell; Daisy Clemmons; Joann Clemmons; Tim Sabutis; Adeline Rosenberg; Jennifer Graves; Michael L Sweeney; John Kramer; Marina Ziehn; Brandon Brown; Jamie L Weiss; Ahmed Z Obeidat
Journal:  Neurol Ther       Date:  2022-05-24

3.  Knowledge Is Power, but Is Ignorance Bliss? Optimising Conversations About Disease Progression in Multiple Sclerosis.

Authors:  Patrick Vermersch; Jane Shanahan; Dawn Langdon; David Yeandle; Nektaria Alexandri; Sven Schippling
Journal:  Neurol Ther       Date:  2019-11-20

Review 4.  Disease Progression in Multiple Sclerosis: A Literature Review Exploring Patient Perspectives.

Authors:  Elisabeth G Celius; Heidi Thompson; Maija Pontaga; Dawn Langdon; Alice Laroni; Stanca Potra; Trishna Bharadia; David Yeandle; Jane Shanahan; Pieter van Galen; Nektaria Alexandri; Jürg Kesselring
Journal:  Patient Prefer Adherence       Date:  2021-01-08       Impact factor: 2.711

5.  Patient and physician preferences for multiple sclerosis treatments in Germany: A discrete-choice experiment study.

Authors:  Christine Poulos; Craig Wakeford; Elizabeth Kinter; Brennan Mange; Thomas Schenk; Mehul Jhaveri
Journal:  Mult Scler J Exp Transl Clin       Date:  2020-03-08
  5 in total

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