Literature DB >> 30567256

Potassium chloride mixture may maintain hypokalaemia and hypertension.

Mette Johannsen Mandoe1, Rikke Borg2,3, Ditte Hansen1,3.   

Abstract

Hypokalaemia can be treated with potassium chloride mixture. Some mixtures contain liquorice extract (glycyrrhizin) as a supplement to improve taste. Glycyrrhizin can cause pseudohyperaldosteronism and thereby result in hypertension and hypokalaemia. We here present a case where treatment with potassium chloride mixture causes hypertension and hypokalaemia in a 50-year-old woman. After unravelling differential diagnosis, the potassium chloride mixture was stopped. After the discontinuation, the patient's blood pressure was well managed and the potassium levels normalised. © BMJ Publishing Group Limited 2018. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  cardiovascular system; contraindications and precautions; endocrine system; fluid electrolyte and acid-base disturbances; hypertension

Mesh:

Substances:

Year:  2018        PMID: 30567256      PMCID: PMC6301460          DOI: 10.1136/bcr-2017-223732

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  6 in total

1.  The determination of glycyrrhizin in selected UK liquorice products.

Authors:  E A Spinks; G R Fenwick
Journal:  Food Addit Contam       Date:  1990 Nov-Dec

2.  Licorice-induced hypermineralocorticoidism.

Authors:  R V Farese; E G Biglieri; C H Shackleton; I Irony; R Gomez-Fontes
Journal:  N Engl J Med       Date:  1991-10-24       Impact factor: 91.245

3.  Too much of a good thing: a woman with hypertension and hypokalemia.

Authors:  Sean C Murphy; Sean Agger; Petrie M Rainey
Journal:  Clin Chem       Date:  2009-12       Impact factor: 8.327

4.  Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated.

Authors:  J W Funder; P T Pearce; R Smith; A I Smith
Journal:  Science       Date:  1988-10-28       Impact factor: 47.728

5.  Licorice abuse: time to send a warning message.

Authors:  Hesham R Omar; Irina Komarova; Mohamed El-Ghonemi; Ahmed Fathy; Rania Rashad; Hany D Abdelmalak; Muralidhar Reddy Yerramadha; Yaseen Ali; Engy Helal; Enrico M Camporesi
Journal:  Ther Adv Endocrinol Metab       Date:  2012-08       Impact factor: 3.565

6.  Liquorice toxicity and the renin-angiotensin-aldosterone axis in man.

Authors:  M T Epstein; E A Espiner; R A Donald; H Hughes
Journal:  Br Med J       Date:  1977-01-22
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.