| Literature DB >> 30565539 |
Gin S Malhi1, Pritha Das2, Zola Mannie3, Lauren Irwin4.
Abstract
Treatment-resistant depression is widely defined as non-response to two 'adequate' courses of treatment. However, the definitions of treatment and depression are inconsistent reflecting gaps in our understanding. We argue that a failure to respond is often the result of administering inappropriate treatment, which occurs principally because of paradigm failure.Declaration of interestNone.Entities:
Keywords: Depressive disorders; antidepressants; bipolar affective disorders; treatment
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Year: 2019 PMID: 30565539 DOI: 10.1192/bjp.2018.246
Source DB: PubMed Journal: Br J Psychiatry ISSN: 0007-1250 Impact factor: 9.319