Literature DB >> 3056427

Activation of immune responses by muroctasin.

M Akasaki1.   

Abstract

N2-[(N-Acetylmuramoyl)-L-alanyl-D-isoglutaminyl]-N6-stearoyl-L-lysine (MDP-Lys(L18), muroctasin), a muramyl dipeptide derivative, has been reported to enhance host resistance to infections, as well as displaying adjuvant activities on the humoral and cellular immune responses. This paper reviews briefly its immunopotentiating activities, which were found to be attributed to its augmenting effect on interleukin 1 production.

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Year:  1988        PMID: 3056427

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


  2 in total

1.  Synergistic effects of romurtide and cefmenoxime against experimental Klebsiella pneumonia in mice.

Authors:  O Tatara; C Nakahama; Y Niki
Journal:  Antimicrob Agents Chemother       Date:  1992-01       Impact factor: 5.191

2.  Apyrogenic synthetic desmuramyldipeptide, LK-409, with immunomodulatory properties.

Authors:  M Sollner; V Kotnik; S Pecar; A Stace; S Simcic; L Povsic; B Herzog-Wraber; L Klampfer; A Ihan; P Grosman
Journal:  Agents Actions       Date:  1993-03
  2 in total

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