| Literature DB >> 30561563 |
Sabelle Jallow1,2,3, Yasmeen Agosti1,2, Prudence Kgagudi1,2, Megan Vandecar3, Clare L Cutland1,2, Eric A F Simões1,4, Marta C Nunes1,2, Melinda S Suchard3, Shabir A Madhi1,2.
Abstract
Human immunodeficiency virus (HIV)-exposed, uninfected infants have higher risks of respiratory syncytial virus-associated hospitalization than HIV-unexposed infants. Despite similar neutralizing antibody titers between HIV-infected and -uninfected women, maternal HIV infection and hypergammaglobulinemia were independently associated with lower titers in newborns. Maternal hypergammaglobulinemia was associated with lower cord-to-maternal antibody ratio.Entities:
Keywords: RSV neutralizing antibody; human immunodeficiency virus; lower respiratory tract infection; maternal immunization; respiratory syncytial virus
Year: 2019 PMID: 30561563 DOI: 10.1093/cid/ciy1071
Source DB: PubMed Journal: Clin Infect Dis ISSN: 1058-4838 Impact factor: 9.079