| Literature DB >> 30559134 |
Arash Heidari1,2, Miriam Quinlan1, David J Benjamin3, Brett Laurence4, Anandit Mu5, Tiffany Ngai5, Wes J Hoffman6, Stuart H Cohen7, Ian McHardy8, Royce Johnson1,2, George R Thompson9,8.
Abstract
Patients with coccidioidal meningitis require lifelong antifungal therapy. Cumulative toxicity and lack of antifungal efficacy require salvage therapy in the treatment of some patients. In a retrospective review of nine patients with coccidioidal meningitis treated with isavuconazole, successful therapy was seen in three patients and stable disease was confirmed in six patients. Isavuconazole may be a useful addition to the therapeutic choices currently available for coccidioidal meningitis.Entities:
Keywords: coccidioides; isavuconazole; meningitis
Mesh:
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Year: 2019 PMID: 30559134 PMCID: PMC6395935 DOI: 10.1128/AAC.02232-18
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191