Literature DB >> 30556056

The Role of Platelets in Ischemic Conditioning.

Juan Alpuche1,2, Luz Quírino2,3, José T Sánchez-Vega4, Jonathan Yap5, Eduardo Pérez-Campos2,6, Hector A Cabrera-Fuentes7,8,9,10,11.   

Abstract

Ischemic heart disease (IHD) is one of the leading causes of death and disability worldwide. Platelets, as the main regulators of hemostasis, are major players in acute myocardial ischemia/reperfusion injury (IRI). Additionally, platelets are modified by endogenous cardioprotective strategies such as ischemic preconditioning, postconditioning, and remote ischemic conditioning. In this article, we provide an overview of the functionional role of platelets in acute myocardial IRI, and highlight their potential as targets for cardioprotection to improve health outcomes in patients with IHD.

Entities:  

Keywords:  cardioprotection; ischemia-reperfusion injury; ischemic conditioning; platelets

Year:  2018        PMID： 30556056      PMCID： PMC6291202     

Source DB:  PubMed          Journal:  Cond Med        ISSN： 2577-3240


  2 in total

1.  Targeting Mitochondrial Fission Using Mdivi-1 in A Clinically Relevant Large Animal Model of Acute Myocardial Infarction: A Pilot Study.

Authors:  Sang-Bing Ong; Xiu-Yi Kwek; Khairunnisa Katwadi; Sauri Hernandez-Resendiz; Gustavo E Crespo-Avilan; Nur Izzah Ismail; Ying-Hsi Lin; En Ping Yap; Song-Yi Lim; K P Myu Mai Ja; Chrishan J A Ramachandra; Nicole Tee; Jin Jiat Toh; Winston Shim; Philip Wong; Hector A Cabrera-Fuentes; Derek J Hausenloy
Journal:  Int J Mol Sci       Date:  2019-08-15       Impact factor: 5.923

Review 2.  Remote ischaemic conditioning for stroke: unanswered questions and future directions.

Authors:  Sheharyar Baig; Bethany Moyle; Krishnan Padmakumari Sivaraman Nair; Jessica Redgrave; Arshad Majid; Ali Ali
Journal:  Stroke Vasc Neurol       Date:  2021-04-26
  2 in total

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