Literature DB >> 30551869

Fighting Cancer Using an Oncofetal Glycosaminoglycan-Binding Protein from Malaria Parasites.

Mette Ø Agerbæk1, Sara Bang-Christensen1, Ali Salanti2.   

Abstract

Malaria research has led to the discovery of oncofetal chondroitin sulfate, which appears to be shared between placental trophoblasts and cancer cells and can be detected by the evolutionary refined malaria protein VAR2CSA. Interestingly, using recombinant VAR2CSA to target oncofetal chondroitin sulfate shows promise for novel cancer diagnostics and therapeutics.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  VAR2CSA; cancer; oncofetal chondroitin sulfate; placental malaria

Mesh：

Substances：

Year:  2018        PMID： 30551869     DOI： 10.1016/j.pt.2018.11.004

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN： 1471-4922


  9 in total

1.  Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA.

Authors:  Rui Ma; Tengfei Lian; Rick Huang; Jonathan P Renn; Jennifer D Petersen; Joshua Zimmerberg; Patrick E Duffy; Niraj H Tolia
Journal:  Nat Microbiol       Date:  2021-01-15       Impact factor: 17.745

2.  Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein.

Authors:  Sara R Bang-Christensen; Rasmus S Pedersen; Marina A Pereira; Thomas M Clausen; Caroline Løppke; Nicolai T Sand; Theresa D Ahrens; Amalie M Jørgensen; Yi Chieh Lim; Louise Goksøyr; Swati Choudhary; Tobias Gustavsson; Robert Dagil; Mads Daugaard; Adam F Sander; Mathias H Torp; Max Søgaard; Thor G Theander; Olga Østrup; Ulrik Lassen; Petra Hamerlik; Ali Salanti; Mette Ø Agerbæk
Journal:  Cells       Date:  2019-08-28       Impact factor: 6.600

Review 3.  Magnetic Particles for CTC Enrichment.

Authors:  Peng Liu; Pascal Jonkheijm; Leon W M M Terstappen; Michiel Stevens
Journal:  Cancers (Basel)       Date:  2020-11-26       Impact factor: 6.639

4.  The transcriptomic profiling of SARS-CoV-2 compared to SARS, MERS, EBOV, and H1N1.

Authors:  Alsamman M Alsamman; Hatem Zayed
Journal:  PLoS One       Date:  2020-12-10       Impact factor: 3.240

5.  Allelic variants of full-length VAR2CSA, the placental malaria vaccine candidate, differ in antigenicity and receptor binding affinity.

Authors:  Jonathan P Renn; Justin Y A Doritchamou; Bergeline C Nguemwo Tentokam; Robert D Morrison; Matthew V Cowles; Martin Burkhardt; Rui Ma; Almahamoudou Mahamar; Oumar Attaher; Bacary S Diarra; Moussa Traore; Alassane Dicko; Niraj H Tolia; Michal Fried; Patrick E Duffy
Journal:  Commun Biol       Date:  2021-11-19

Review 6.  Emulating interactions between microorganisms and tumor microenvironment to develop cancer theranostics.

Authors:  Tongmeng Jiang; Tao Yang; Yingfan Chen; Yao Miao; Yajing Xu; Honglin Jiang; Mingying Yang; Chuanbin Mao
Journal:  Theranostics       Date:  2022-03-14       Impact factor: 11.600

Review 7.  Fusobacterium nucleatum and cancer.

Authors:  Tamar Alon-Maimon; Ofer Mandelboim; Gilad Bachrach
Journal:  Periodontol 2000       Date:  2022-03-04       Impact factor: 12.239

8.  Optimization of rVAR2-Based Isolation of Cancer Cells in Blood for Building a Robust Assay for Clinical Detection of Circulating Tumor Cells.

Authors:  Nicolai T Sand; Tobias B Petersen; Sara R Bang-Christensen; Theresa D Ahrens; Caroline Løppke; Amalie M Jørgensen; Tobias Gustavsson; Swati Choudhary; Thor G Theander; Ali Salanti; Mette Ø Agerbæk
Journal:  Int J Mol Sci       Date:  2020-03-31       Impact factor: 5.923

Review 9.  From "Serum Sickness" to "Xenosialitis": Past, Present, and Future Significance of the Non-human Sialic Acid Neu5Gc.

Authors:  Chirag Dhar; Aniruddha Sasmal; Ajit Varki
Journal:  Front Immunol       Date:  2019-04-17       Impact factor: 7.561
  9 in total

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