Current status of laparoscopic surgery for colorectal cancer based on the evidence of JCOG0404 trial.

The concept of optimal surgery for colorectal cancer in Japan includes D3 dissection, which preserves the mesocolic plane by sharp dissection off the parietal plane, with central vascular ligation. In recent 25 years, laparoscopic surgery for colorectal cancers has been widespread, and Japan Society for Endoscopic Surgery(JSES) demonstrated that a penetration rate of laparoscopic surgery for colorectal cancer was 58 % in 2013. To evaluate long and short-term outcomes of laparoscopic D3 resection for stage Il/III colorectal cancer, a randomized con- trolled trial was conducted in Japan (JCOG0404). The evidence based on JCOG0404 trial would contribute to the appropriate development of laparoscopic surgery with technical and oncological safety in Japan.

RCT Entities:   Population Interventions Outcomes