| Literature DB >> 30547438 |
Salvatore Alaimo1, Alfredo Pulvirenti2.
Abstract
The wealth of knowledge and omic data available in drug research allowed the rising of several computational methods in drug discovery field yielding a novel and exciting application called drug repositioning. Several computational methods try to make a high-level integration of all the knowledge in order to discover unknown mechanisms. In this chapter we present an in-depth review of data resources and computational models for drug repositioning.Keywords: Drug repositioning; Drug-target interaction prediction; Interaction networks; Network-based drug repurposing; Precision medicine
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Year: 2019 PMID： 30547438 DOI： 10.1007/978-1-4939-8955-3_6
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745