G N Sanjeeva1, M Sahana2, H B Pavithra2, V H T Swamy3, B R Srirama3, D R Sunil Kumar4, Lalitha Hande5, S N Mothi3. 1. Pediatric Center of Excellence, Indira Gandhi Institute of Child Health, Dharmaram College Post, South Hospital Complex, Bangalore 560 029, Karnataka, India. sanju.gn26@gmail.com. 2. Pediatric Center of Excellence, Indira Gandhi Institute of Child Health, Dharmaram College Post, South Hospital Complex, Bangalore 560 029, Karnataka, India. 3. Asha Kirana Hospital, Hebbal Industrial Housing Area, Ring Road, Hebbal, Mysore 570016, Karnataka, India. 4. National AIDS Control Organization, Ministry of Health and Family Welfare, New Delhi, India. 5. Department of Health and Family Welfare, Karnataka State AIDS Prevention Society, Bangalore, Karnataka, India.
Abstract
OBJECTIVES: In India, access to free anti-retroviral therapy has improved the survival of perinatally human immunodeficiency virus (HIV) infected children resulting in the transition of many such children to adulthood. This study aims to understand the social-outcomes and quality of life (QOL) among these adults. METHODS: This cross-sectional study was conducted in two tertiary HIV care centers in south India. Perinatally HIV-infected adults aged >18 y were enrolled after obtaining consent. Data were collected by questionnaire based interviews for social outcomes and WHO Quality of Life-BREF (WHOQOL-BREF) for QOL. The social-outcome indicators monitored pertained to family support, educational qualification and occupational, economic, and marital status. RESULTS: The mean age of 107 participants was 18·9 ± 1·1y. The school drop-out rate was 58%. Sixty-two percent were double orphans. Forty-three-percent of the participants were employed with mean per-capita monthly income of Rs.4105 ± 2979 ($65·2 ± 47·3). Fourteen-percent of the participants were married, or in a relationship, and a majority of them, 93%, were females. For QOL, the mean raw score was highest for social relationship (15·79). Relative to studying subjects, a higher proportion of school dropouts scored poorly in social relationship (42% vs.14·8%; Chi-square = 5·28; p = 0·02) and environmental QOL (46% vs.19·6%;Chi-square = 8·09; p = 0·004). The proportion of subjects with a poor physical health QOL was higher among those with a per-capita monthly income above the national average than those with below the national average (69% vs.33·3%; Chi-square = 5·27; p = 0·02). CONCLUSIONS: Though clinico-immunological disease was stable in these perinatally HIV-infected young adults, their social-outcomes pertaining to education, occupation, income, and family support were poor. Factors like education, parental care, and income of the subjects were associated with poor QOL.
OBJECTIVES: In India, access to free anti-retroviral therapy has improved the survival of perinatally human immunodeficiency virus (HIV) infectedchildren resulting in the transition of many such children to adulthood. This study aims to understand the social-outcomes and quality of life (QOL) among these adults. METHODS: This cross-sectional study was conducted in two tertiary HIV care centers in south India. Perinatally HIV-infected adults aged >18 y were enrolled after obtaining consent. Data were collected by questionnaire based interviews for social outcomes and WHO Quality of Life-BREF (WHOQOL-BREF) for QOL. The social-outcome indicators monitored pertained to family support, educational qualification and occupational, economic, and marital status. RESULTS: The mean age of 107 participants was 18·9 ± 1·1y. The school drop-out rate was 58%. Sixty-two percent were double orphans. Forty-three-percent of the participants were employed with mean per-capita monthly income of Rs.4105 ± 2979 ($65·2 ± 47·3). Fourteen-percent of the participants were married, or in a relationship, and a majority of them, 93%, were females. For QOL, the mean raw score was highest for social relationship (15·79). Relative to studying subjects, a higher proportion of school dropouts scored poorly in social relationship (42% vs.14·8%; Chi-square = 5·28; p = 0·02) and environmental QOL (46% vs.19·6%;Chi-square = 8·09; p = 0·004). The proportion of subjects with a poor physical health QOL was higher among those with a per-capita monthly income above the national average than those with below the national average (69% vs.33·3%; Chi-square = 5·27; p = 0·02). CONCLUSIONS: Though clinico-immunological disease was stable in these perinatally HIV-infected young adults, their social-outcomes pertaining to education, occupation, income, and family support were poor. Factors like education, parental care, and income of the subjects were associated with poor QOL.
Entities:
Keywords:
India; Perinatally HIV-infected adults; Quality of life; Social outcomes
Authors: Agnieszka Matuszewska; Beata Nowak; Wojciech Niżański; Maria Eberhardt; Kinga Domrazek; Anna Nikodem; Benita Wiatrak; Krzysztof Zduniak; Kamil Olejnik; Anna Merwid-Ląd; Tomasz Tomkalski; Diana Jędrzejuk; Ewa Szeląg; Marzenna Podhorska-Okołów; Aleksandra Piotrowska; Izabela Jęśkowiak; Agata Heinrich; Maria Rutkowska; Wojciech Dziewiszek; Tomasz Sozański; Joanna Kwiatkowska; Paulina Jawień; Marek Bolanowski; Adam Szeląg Journal: Oxid Med Cell Longev Date: 2021-07-29 Impact factor: 6.543