Literature DB >> 30547115

An epidural steroid injection in the 6 months preceding a lumbar decompression without fusion predisposes patients to post-operative infections.

Chester J Donnally1, Augustus J Rush1, Sebastian Rivera1, Rushabh M Vakharia2, Ajit M Vakharia3, Dustin H Massel2, Frank J Eismont1.   

Abstract

BACKGROUND: To determine if the timing of a lumbar epidural steroid injection (LESI) effects rates of post-operative infection in patients receiving a non-fusion lumbar decompression (LDC) due to degenerative disc disease (DDD). Lumbar pain due to DDD can frequently be temporized or definitively treated with epidural injections. While there is ample literature regarding the infection risks associated with corticosteroid injections prior to hip/knee replacements, there are few studies relating to the spine.
METHODS: A nationwide insurance database was queried to identify those who underwent LDC for DDD without instrumentation [2005-2014]. Lumbar fusion procedures were excluded. From this group those with a history of a LESI were identified and matched to a control group without a history of LESI. Four separate cohorts were examined: (I) LDC and no LESI within 6 months (control); (II) LDC performed within 0-1 month after LESI; (III) LDC between 1 and 3 months after LESI; (IV) LDC performed between 3 and 6 months after LESI.
RESULTS: There was an increased odds of a 90-day postoperative infection if the LESI was within the 1-3 months (OR =4.69; P<0.001) and 3-6 months (OR =5.33; P<0.001) interval prior to the LDC.
CONCLUSIONS: While LESI is helpful for possibly delaying or avoid lumbar surgery, it may predispose patients to higher infection rates following lumbar decompressions without fusion. Surgeons and pain management specialist should counsel patients on these risks and.

Entities:  

Keywords:  Lumbar decompression; epidural injection; infection; lumbar epidural steroid injection (LESI); postoperative complications; spine surgery

Year:  2018        PMID: 30547115      PMCID: PMC6261770          DOI: 10.21037/jss.2018.09.05

Source DB:  PubMed          Journal:  J Spine Surg        ISSN: 2414-4630


  25 in total

1.  The Timing of Total Hip Arthroplasty After Intraarticular Hip Injection Affects Postoperative Infection Risk.

Authors:  Brian C Werner; Jourdan M Cancienne; James A Browne
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2.  Effects of epidural steroids on lumbar dura material properties.

Authors:  A V Slucky; M S Sacks; V S Pallares; T I Malinin; F J Eismont
Journal:  J Spinal Disord       Date:  1999-08

3.  The effect of preoperative lumbar epidural corticosteroid injection on postoperative infection rate in patients undergoing single-level lumbar decompression.

Authors:  Jonathan G Seavey; George C Balazs; Theodore Steelman; Melvin Helgeson; David E Gwinn; Scott C Wagner
Journal:  Spine J       Date:  2017-04-17       Impact factor: 4.166

4.  Spinal subdural abscess following epidural steroid injection.

Authors:  Matthew J Kraeutler; Joseph D Bozzay; Matthew P Walker; Kuruvilla John
Journal:  J Neurosurg Spine       Date:  2015-01

5.  Rates of infection after spine surgery based on 108,419 procedures: a report from the Scoliosis Research Society Morbidity and Mortality Committee.

Authors:  Justin S Smith; Christopher I Shaffrey; Charles A Sansur; Sigurd H Berven; Kai-Ming G Fu; Paul A Broadstone; Theodore J Choma; Michael J Goytan; Hilali H Noordeen; Dennis R Knapp; Robert A Hart; William F Donaldson; David W Polly; Joseph H Perra; Oheneba Boachie-Adjei
Journal:  Spine (Phila Pa 1976)       Date:  2011-04-01       Impact factor: 3.468

6.  The impact of preoperative epidural injections on postoperative infection in lumbar fusion surgery.

Authors:  Anuj Singla; Scott Yang; Brian C Werner; Jourdan M Cancienne; Ali Nourbakhsh; Adam L Shimer; Hamid Hassanzadeh; Francis H Shen
Journal:  J Neurosurg Spine       Date:  2017-03-14

7.  Analysis of the growth of epidural injections and costs in the Medicare population: a comparative evaluation of 1997, 2002, and 2006 data.

Authors:  Laxmaiah Manchikanti; Vidyasagar Pampati; Mark V Boswell; Howard S Smith; Joshua A Hirsch
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8.  Epidural steroid injection-related events requiring hospitalisation or emergency room visits among 52,935 procedures performed at a single centre.

Authors:  Joon Woo Lee; Eugene Lee; Guen Young Lee; Yusuhn Kang; Joong Mo Ahn; Heung Sik Kang
Journal:  Eur Radiol       Date:  2017-07-19       Impact factor: 5.315

9.  Intraoperative Corticosteroid Injection at the Time of Knee Arthroscopy Is Associated With Increased Postoperative Infection Rates in a Large Medicare Population.

Authors:  Jourdan M Cancienne; F Winston Gwathmey; Brian C Werner
Journal:  Arthroscopy       Date:  2015-11-06       Impact factor: 4.772

10.  Cervical Meningomyelitis After Lumbar Epidural Steroid Injection.

Authors:  Yujin Lee; Joon-Sung Kim; Ji Yeon Kim
Journal:  Ann Rehabil Med       Date:  2015-06-30
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  3 in total

1.  Infection Risk of Lumbar Epidural Injection in the Operating Theatre Prior to Lumbar Fusion Surgery.

Authors:  Peng Li; Xiuwei Hou; Lifeng Gao; Xiaochen Zheng
Journal:  J Pain Res       Date:  2020-08-26       Impact factor: 3.133

2.  Pain Management During COVID-19 and Steroids: Striking a Balance.

Authors:  Steven P Cohen; W Michael Hooten; Christopher R Phillips
Journal:  Pain Med       Date:  2020-08-01       Impact factor: 3.750

3.  The Impact of Corticosteroid Injection Timing on Infection Rates Following Spine Surgery: A Systematic Review and Meta-Analysis.

Authors:  Gregory S Kazarian; Michael E Steinhaus; Han Jo Kim
Journal:  Global Spine J       Date:  2021-09-26
  3 in total

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