Literature DB >> 30545928

New molecular and therapeutic insights into canine diffuse large B-cell lymphoma elucidates the role of the dog as a model for human disease.

Luca Aresu1, Serena Ferraresso2, Laura Marconato3, Luciano Cascione4,5, Sara Napoli4, Eugenio Gaudio4, Ivo Kwee4,5,6, Chiara Tarantelli4, Andrea Testa7, Chiara Maniaci7,8, Alessio Ciulli7, Petra Hillmann9, Thomas Bohnacker10, Matthias P Wymann10, Stefano Comazzi11, Massimo Milan2, Fulvio Riondato12, Giulia Dalla Rovere2, Mery Giantin2, Diana Giannuzzi2, Francesco Bertoni13.   

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Year:  2018        PMID: 30545928      PMCID: PMC6545862          DOI: 10.3324/haematol.2018.207027

Source DB:  PubMed          Journal:  Haematologica        ISSN: 0390-6078            Impact factor:   9.941


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  14 in total

1.  Enforced expression of Lin28b leads to impaired T-cell development, release of inflammatory cytokines, and peripheral T-cell lymphoma.

Authors:  Sarah H Beachy; Masahiro Onozawa; Yang Jo Chung; Chris Slape; Sven Bilke; Princy Francis; Marbin Pineda; Robert L Walker; Paul Meltzer; Peter D Aplan
Journal:  Blood       Date:  2012-06-21       Impact factor: 22.113

2.  ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets.

Authors:  Andrew J Souers; Joel D Leverson; Erwin R Boghaert; Scott L Ackler; Nathaniel D Catron; Jun Chen; Brian D Dayton; Hong Ding; Sari H Enschede; Wayne J Fairbrother; David C S Huang; Sarah G Hymowitz; Sha Jin; Seong Lin Khaw; Peter J Kovar; Lloyd T Lam; Jackie Lee; Heather L Maecker; Kennan C Marsh; Kylie D Mason; Michael J Mitten; Paul M Nimmer; Anatol Oleksijew; Chang H Park; Cheol-Min Park; Darren C Phillips; Andrew W Roberts; Deepak Sampath; John F Seymour; Morey L Smith; Gerard M Sullivan; Stephen K Tahir; Chris Tse; Michael D Wendt; Yu Xiao; John C Xue; Haichao Zhang; Rod A Humerickhouse; Saul H Rosenberg; Steven W Elmore
Journal:  Nat Med       Date:  2013-01-06       Impact factor: 53.440

3.  The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy.

Authors:  Lee A Honigberg; Ashley M Smith; Mint Sirisawad; Erik Verner; David Loury; Betty Chang; Shyr Li; Zhengying Pan; Douglas H Thamm; Richard A Miller; Joseph J Buggy
Journal:  Proc Natl Acad Sci U S A       Date:  2010-07-06       Impact factor: 11.205

4.  PQR309 Is a Novel Dual PI3K/mTOR Inhibitor with Preclinical Antitumor Activity in Lymphomas as a Single Agent and in Combination Therapy.

Authors:  Chiara Tarantelli; Eugenio Gaudio; Alberto J Arribas; Ivo Kwee; Petra Hillmann; Andrea Rinaldi; Luciano Cascione; Filippo Spriano; Elena Bernasconi; Francesca Guidetti; Laura Carrassa; Roberta Bordone Pittau; Florent Beaufils; Reto Ritschard; Denise Rageot; Alexander Sele; Barbara Dossena; Francesca Maria Rossi; Antonella Zucchetto; Monica Taborelli; Valter Gattei; Davide Rossi; Anastasios Stathis; Georg Stussi; Massimo Broggini; Matthias P Wymann; Andreas Wicki; Emanuele Zucca; Vladimir Cmiljanovic; Doriano Fabbro; Francesco Bertoni
Journal:  Clin Cancer Res       Date:  2017-10-24       Impact factor: 12.531

5.  Genetic inactivation of TRAF3 in canine and human B-cell lymphoma.

Authors:  Kevin R Bushell; Yukyoung Kim; Fong Chun Chan; Susana Ben-Neriah; Andrew Jenks; Miguel Alcaide; Daniel Fornika; Bruno M Grande; Sarah Arthur; Randy D Gascoyne; Christian Steidl; Ryan D Morin
Journal:  Blood       Date:  2014-12-02       Impact factor: 22.113

6.  Randomized, placebo-controlled, double-blinded chemoimmunotherapy clinical trial in a pet dog model of diffuse large B-cell lymphoma.

Authors:  Laura Marconato; Patrick Frayssinet; Nicole Rouquet; Stefano Comazzi; Vito Ferdinando Leone; Paola Laganga; Federica Rossi; Massimo Vignoli; Lorenzo Pezzoli; Luca Aresu
Journal:  Clin Cancer Res       Date:  2013-12-03       Impact factor: 12.531

Review 7.  Genetics of diffuse large B-cell lymphoma.

Authors:  Laura Pasqualucci; Riccardo Dalla-Favera
Journal:  Blood       Date:  2018-04-17       Impact factor: 25.476

8.  Preclinical Evaluation of the Novel BTK Inhibitor Acalabrutinib in Canine Models of B-Cell Non-Hodgkin Lymphoma.

Authors:  Bonnie K Harrington; Heather L Gardner; Raquel Izumi; Ahmed Hamdy; Wayne Rothbaum; Kevin R Coombes; Todd Covey; Allard Kaptein; Michael Gulrajani; Bart Van Lith; Cecile Krejsa; Christopher C Coss; Duncan S Russell; Xiaoli Zhang; Bridget K Urie; Cheryl A London; John C Byrd; Amy J Johnson; William C Kisseberth
Journal:  PLoS One       Date:  2016-07-19       Impact factor: 3.240

9.  DNA methylation profiling reveals common signatures of tumorigenesis and defines epigenetic prognostic subtypes of canine Diffuse Large B-cell Lymphoma.

Authors:  Serena Ferraresso; Arianna Aricò; Tiziana Sanavia; Silvia Da Ros; Massimo Milan; Luciano Cascione; Stefano Comazzi; Valeria Martini; Mery Giantin; Barbara Di Camillo; Sandro Mazzariol; Diana Giannuzzi; Laura Marconato; Luca Aresu
Journal:  Sci Rep       Date:  2017-09-14       Impact factor: 4.379

10.  Comparative RNA-Seq and microarray analysis of gene expression changes in B-cell lymphomas of Canis familiaris.

Authors:  Marie Mooney; Jeffrey Bond; Noel Monks; Emily Eugster; David Cherba; Pamela Berlinski; Steve Kamerling; Keith Marotti; Heather Simpson; Tony Rusk; Waibhav Tembe; Christophe Legendre; Hollie Benson; Winnie Liang; Craig Paul Webb
Journal:  PLoS One       Date:  2013-04-04       Impact factor: 3.240

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  15 in total

1.  Antitumor activity of the dual BET and CBP/EP300 inhibitor NEO2734.

Authors:  Filippo Spriano; Eugenio Gaudio; Luciano Cascione; Chiara Tarantelli; Federica Melle; Giovanna Motta; Valdemar Priebe; Andrea Rinaldi; Gaetanina Golino; Afua Adjeiwaa Mensah; Luca Aresu; Emanuele Zucca; Stefano Pileri; Michael Witcher; Bill Brown; Claes Wahlestedt; Francis Giles; Anastasios Stathis; Francesco Bertoni
Journal:  Blood Adv       Date:  2020-09-08

2.  The genomic landscape of canine diffuse large B-cell lymphoma identifies distinct subtypes with clinical and therapeutic implications.

Authors:  Diana Giannuzzi; Laura Marconato; Antonella Fanelli; Luca Licenziato; Raffaella De Maria; Andrea Rinaldi; Luca Rotta; Nicole Rouquet; Giovanni Birolo; Piero Fariselli; Afua A Mensah; Francesco Bertoni; Luca Aresu
Journal:  Lab Anim (NY)       Date:  2022-06-20       Impact factor: 12.625

3.  Hypermethylation-Mediated Silencing of CIDEA, MAL and PCDH17 Tumour Suppressor Genes in Canine DLBCL: From Multi-Omics Analyses to Mechanistic Studies.

Authors:  Eleonora Zorzan; Ramy Elgendy; Giorgia Guerra; Silvia Da Ros; Maria Elena Gelain; Federico Bonsembiante; Giulia Garaffo; Nicoletta Vitale; Roberto Piva; Laura Marconato; Luca Aresu; Mauro Dacasto; Mery Giantin
Journal:  Int J Mol Sci       Date:  2022-04-05       Impact factor: 5.923

4.  Mutational landscape of canine B-cell lymphoma profiled at single nucleotide resolution by RNA-seq.

Authors:  Diana Giannuzzi; Laura Marconato; Luciano Cascione; Stefano Comazzi; Ramy Elgendy; Sara Pegolo; Alessio Cecchinato; Francesco Bertoni; Luca Aresu; Serena Ferraresso
Journal:  PLoS One       Date:  2019-04-24       Impact factor: 3.240

5.  Fido-SNP: the first webserver for scoring the impact of single nucleotide variants in the dog genome.

Authors:  Emidio Capriotti; Ludovica Montanucci; Giuseppe Profiti; Ivan Rossi; Diana Giannuzzi; Luca Aresu; Piero Fariselli
Journal:  Nucleic Acids Res       Date:  2019-07-02       Impact factor: 16.971

6.  Opportunities and challenges of active immunotherapy in dogs with B-cell lymphoma: a 5-year experience in two veterinary oncology centers.

Authors:  Laura Marconato; Luca Aresu; Damiano Stefanello; Stefano Comazzi; Valeria Martini; Roberta Ferrari; Fulvio Riondato; Nicole Rouquet; Patrick Frayssinet; Silvia Sabattini
Journal:  J Immunother Cancer       Date:  2019-06-07       Impact factor: 13.751

Review 7.  Is There a Role for Dual PI3K/mTOR Inhibitors for Patients Affected with Lymphoma?

Authors:  Chiara Tarantelli; Antonio Lupia; Anastasios Stathis; Francesco Bertoni
Journal:  Int J Mol Sci       Date:  2020-02-05       Impact factor: 5.923

Review 8.  The Genetic and Molecular Basis for Canine Models of Human Leukemia and Lymphoma.

Authors:  Anne C Avery
Journal:  Front Oncol       Date:  2020-01-24       Impact factor: 6.244

9.  Phenotypical Characterization and Clinical Outcome of Canine Burkitt-Like Lymphoma.

Authors:  Luca Aresu; Chiara Agnoli; Arturo Nicoletti; Antonella Fanelli; Valeria Martini; Francesco Bertoni; Laura Marconato
Journal:  Front Vet Sci       Date:  2021-03-17

10.  Long Non-Coding RNAs as Molecular Signatures for Canine B-Cell Lymphoma Characterization.

Authors:  Luciano Cascione; Luca Giudice; Serena Ferraresso; Laura Marconato; Diana Giannuzzi; Sara Napoli; Francesco Bertoni; Rosalba Giugno; Luca Aresu
Journal:  Noncoding RNA       Date:  2019-09-19
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