Nader Shaikh1, Ellen R Wald2, Jong-Hyeon Jeong3, Marcia Kurs-Lasky4, David Nash5, Michael E Pichichero6, Diana H Kearney4, Mary Ann Haralam4, A'Delbert Bowen7, Lynda L Flom7, Alejandro Hoberman4. 1. Division of General Academic Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address: nader.shaikh@chp.edu. 2. Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI. 3. Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA. 4. Division of General Academic Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA. 5. Division of Allergy and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA. 6. Pediatric Infectious Diseases, Rochester General Research Institute, Rochester, NY. 7. Division of Pediatric Radiology, Children's Hospital of Pittsburgh, Pittsburgh, PA.
Abstract
OBJECTIVE: To develop a parent-reported Pediatric Rhinosinusitis Symptom Scale (PRSS) that could be used to monitor symptoms of young children with acute sinusitis in response to therapy. STUDY DESIGN: We developed an 8-item symptom severity scale and evaluated its internal reliability, construct validity, and responsiveness in children 2-12 years of age with acute sinusitis. Parents of 258 children with acute sinusitis completed the PRSS at the time of diagnosis, as a diary at home, and at the follow-up visit at days 10-12. Based on psychometric results and additional parent feedback, we revised the scale. We evaluated the revised version in 185 children with acute sinusitis. RESULTS: Correlations between the scale and reference measures on the day of enrollment were in the expected direction and of the expected magnitude. PRSS scores at the time of presentation correlated with radiographic findings (P < .001), functional status (P < .001), and parental assessment of overall symptom severity (P < .001). Responsiveness (standardized response mean) and test-retest reliability of the revised scale were good (2.17 and 0.75, respectively). CONCLUSIONS: We have developed an outcome measure to track the symptoms of acute sinusitis. Data presented here support the use of the PRSS as a measure of change in symptom burden in clinical trials of children with acute sinusitis.
OBJECTIVE: To develop a parent-reported Pediatric Rhinosinusitis Symptom Scale (PRSS) that could be used to monitor symptoms of young children with acute sinusitis in response to therapy. STUDY DESIGN: We developed an 8-item symptom severity scale and evaluated its internal reliability, construct validity, and responsiveness in children 2-12 years of age with acute sinusitis. Parents of 258 children with acute sinusitis completed the PRSS at the time of diagnosis, as a diary at home, and at the follow-up visit at days 10-12. Based on psychometric results and additional parent feedback, we revised the scale. We evaluated the revised version in 185 children with acute sinusitis. RESULTS: Correlations between the scale and reference measures on the day of enrollment were in the expected direction and of the expected magnitude. PRSS scores at the time of presentation correlated with radiographic findings (P < .001), functional status (P < .001), and parental assessment of overall symptom severity (P < .001). Responsiveness (standardized response mean) and test-retest reliability of the revised scale were good (2.17 and 0.75, respectively). CONCLUSIONS: We have developed an outcome measure to track the symptoms of acute sinusitis. Data presented here support the use of the PRSS as a measure of change in symptom burden in clinical trials of children with acute sinusitis.
Authors: Marianne de Vries; Rody Ouwendijk; Alphons G Kessels; Michiel W de Haan; Karin Flobbe; Maria G M Hunink; Jos M A van Engelshoven; Patricia J Nelemans Journal: J Vasc Surg Date: 2005-02 Impact factor: 4.268
Authors: Nader Shaikh; Alejandro Hoberman; Jack L Paradise; Howard E Rockette; Marcia Kurs-Lasky; D Kathleen Colborn; Diana H Kearney; Lisa M Zoffel Journal: Pediatr Infect Dis J Date: 2009-01 Impact factor: 2.129
Authors: Dennis A Revicki; David Cella; Ron D Hays; Jeff A Sloan; William R Lenderking; Neil K Aaronson Journal: Health Qual Life Outcomes Date: 2006-09-27 Impact factor: 3.186
Authors: Santiago M C Lopez; Nader Shaikh; Monika Johnson; Hui Liu; Judith M Martin; John V Williams Journal: Front Pediatr Date: 2022-01-12 Impact factor: 3.418