Literature DB >> 3054376

[The prognosis of carcinoid tumors of the stomach].

M Stolte1, D Ebert, E Seifert, F Schulte, J Rode.   

Abstract

Follow-up examinations were carried out in 55 patients with small carcinoid tumours in the stomach (diameter 0.5-1.7 cm). For the most part, the tumours were located within the body and fundus of the stomach, with only 3 being found in the antrum. Thirty-five of the 55 patients (63.6%) had multiple gastric carcinoids, while in 46 patients (83.6%) concomitant chronic atrophic gastritis was also present. Eight patients were treated surgically, while 47 patients were merely kept under endoscopic/bioptic surveillance. In 34 out of 40 patients in whom the diagnosis had been established more than 6 months previously (longest observation period 13 years), follow-up findings were available (7 surgical patients, 27 non-operated patients). The patients submitted to surgery (average follow-up period 3.5 years) are alive and free of complaints between 1 and 9 years post-op; no metastases have occurred, but a recurrent tumour has developed in a single patient. Among the 27 non-operated patients (average follow-up period 3.6 years), 3 have died of diseases unrelated to the carcinoid tumours, in none of the other patients has there been any change in the findings. On the basis of these results it is concluded that, in carcinoid tumours of the stomach with a diameter of less than 1.0 cm, surgical treatment is not absolutely necessary, and that, in comparison with the risks represented by surgical mortality and post operative morbidity, regular endoscopic/bioptic follow-up can be considered to be adequate.

Entities:  

Mesh:

Year:  1988        PMID: 3054376

Source DB:  PubMed          Journal:  Leber Magen Darm        ISSN: 0300-8622


  6 in total

Review 1.  Revised classification of neuroendocrine tumours of the lung, pancreas and gut.

Authors:  C Capella; P U Heitz; H Höfler; E Solcia; G Klöppel
Journal:  Virchows Arch       Date:  1995       Impact factor: 4.064

2.  Observations on relationship between hypergastrinemia, multiple gastric carcinoids, and pancreatic mass.

Authors:  I M Modlin; C J Gilligan; G P Lawton; L H Tang; A B West; R Lindenberg
Journal:  Dig Dis Sci       Date:  1996-01       Impact factor: 3.199

Review 3.  Acid suppression and gastric mucosal cell biology.

Authors:  G Delle Fave; H Helander; S Holt; I M Modlin; R Powers; E Solcia; A Soll; Y Tielemans; N A Wright
Journal:  Dig Dis Sci       Date:  1994-09       Impact factor: 3.199

4.  Pattern of gastric endocrine cells in microcarcinoidosis--an immunohistochemical study of 14 gastric biopsies.

Authors:  P Reinecke; F Borchard
Journal:  Virchows Arch       Date:  1996-07       Impact factor: 4.064

5.  Gastric carcinoids: biologic behavior and prognosis after differentiated treatment in relation to type.

Authors:  Kurt Borch; Bo Ahrén; Håkan Ahlman; Sture Falkmer; Göran Granérus; Lars Grimelius
Journal:  Ann Surg       Date:  2005-07       Impact factor: 12.969

Review 6.  Pathophysiological effects of long-term acid suppression in man.

Authors:  R F McCloy; R Arnold; K D Bardhan; D Cattan; E Klinkenberg-Knol; P N Maton; R H Riddell; P Sipponen; A Walan
Journal:  Dig Dis Sci       Date:  1995-02       Impact factor: 3.199

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.