Literature DB >> 30543534

Prolonged Postoperative Ileus Significantly Increases the Cost of Inpatient Stay for Patients Undergoing Elective Colorectal Surgery: Results of a Multivariate Analysis of Prospective Data at a Single Institution.

Howe Mao1, Tony G E Milne1, Gregory O'Grady1,2, Ryash Vather1, Richard Edlin3, Ian Bissett1,2.   

Abstract

BACKGROUND: Prolonged postoperative ileus is a common major complication after abdominal surgery. Retrospective data suggest that ileus doubles the cost of inpatient stay. However, current economic impact data are based on retrospective studies that rely on clinical coding to diagnose ileus.
OBJECTIVE: The aim of this study was to determine the economic burden of ileus for patients undergoing elective colorectal surgery.
DESIGN: Economic data were audited from a prospective database of patients who underwent surgery at Auckland City Hospital between September 2012 and June 2014. SETTINGS: Auckland City Hospital is a large tertiary referral center, using an enhanced recovery after surgery protocol. PATIENTS: Patients were prospectively diagnosed with prolonged postoperative ileus using a standardized definition. MAIN OUTCOME MEASURES: The cost of inpatient stay was analyzed with regard to patient demographics and operative and postoperative factors. A multivariate analysis was performed to determine the cost of ileus when accounting for other significant covariates.
RESULTS: Economic data were attained from 325 patients, and 88 patients (27%) developed ileus. The median inpatient cost (New Zealand dollars) for patients with prolonged ileus, including complication rates and length of stay, was $27,981 (interquartile range= $20,198 to $42,174) compared with $16,317 (interquartile range = $10,620 to $23,722) for other patients, a 71% increase in cost (p < 0.005). Ileus increased all associated healthcare costs, including medical/nursing care, radiology, medication, laboratory costs, and allied health (p < 0.05). Multivariate analysis showed that ileus remained a significant financial burden (p < 0.005) when considering rates of major complications and length of stay. LIMITATIONS: This is a single-institution study, which may impact the generalizability of our results.
CONCLUSIONS: Prolonged ileus causes a substantial financial burden on the healthcare system, in addition to greater complication rates and length of stay in these patients. This is the first study to assess the financial impact of prolonged ileus, diagnosed prospectively using a standardized definition. See Video Abstract at http://links.lww.com/DCR/A825.

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Year:  2019        PMID: 30543534     DOI: 10.1097/DCR.0000000000001301

Source DB:  PubMed          Journal:  Dis Colon Rectum        ISSN: 0012-3706            Impact factor:   4.585


  13 in total

1.  Risk Factors for Prolonged Postoperative Ileus in Colorectal Surgery: A Systematic Review and Meta-analysis.

Authors:  Andrea Carolina Quiroga-Centeno; Kihara Alejandra Jerez-Torra; Pedro Antonio Martin-Mojica; Sergio Andrés Castañeda-Alfonso; María Emma Castillo-Sánchez; Oscar Fernando Calvo-Corredor; Sergio Alejandro Gómez-Ochoa
Journal:  World J Surg       Date:  2020-05       Impact factor: 3.352

Review 2.  The Role of Inflammatory Mediators in the Development of Gastrointestinal Motility Disorders.

Authors:  Tibor Docsa; Adám Sipos; Charles S Cox; Karen Uray
Journal:  Int J Mol Sci       Date:  2022-06-22       Impact factor: 6.208

3.  Proof-of-concept for intervention to prevent post-operative ileus in patients undergoing ileostomy formation.

Authors:  Anya L Greenberg; Yvonne M Kelly; Ankit Sarin; Madhulika G Varma
Journal:  Perioper Med (Lond)       Date:  2022-07-12

4.  Nomogram to predict prolonged postoperative ileus after gastrectomy in gastric cancer.

Authors:  Wen-Quan Liang; Ke-Cheng Zhang; Jian-Xin Cui; Hong-Qing Xi; Ai-Zhen Cai; Ji-Yang Li; Yu-Hua Liu; Jie Liu; Wang Zhang; Peng-Peng Wang; Bo Wei; Lin Chen
Journal:  World J Gastroenterol       Date:  2019-10-14       Impact factor: 5.742

5.  No Coil® placement in patients undergoing left hemicolectomy and low anterior resection for colorectal cancer.

Authors:  Michele Ammendola; Michele Ruggiero; Carlo Talarico; Riccardo Memeo; Giorgio Ammerata; Antonella Capomolla; Rosalinda Filippo; Roberto Romano; Socrate Pallio; Giuseppe Navarra; Severino Montemurro; Giuseppe Currò
Journal:  World J Surg Oncol       Date:  2020-12-10       Impact factor: 2.754

6.  Risk factors and outcomes associated with postoperative ileus following ileostomy formation: a retrospective study.

Authors:  Anya L Greenberg; Yvonne M Kelly; Rachel E McKay; Madhulika G Varma; Ankit Sarin
Journal:  Perioper Med (Lond)       Date:  2021-12-13

Review 7.  State-of-the-art colorectal disease: postoperative ileus.

Authors:  Nils P Sommer; Reiner Schneider; Sven Wehner; Jörg C Kalff; Tim O Vilz
Journal:  Int J Colorectal Dis       Date:  2021-05-11       Impact factor: 2.571

Review 8.  Comparison of prolonged postoperative ileus between laparoscopic right and left colectomy under enhanced recovery after surgery: a propensity score matching analysis.

Authors:  Zhenmeng Lin; Chunkang Yang; Yi Wang; Mingfang Yan; Huizhe Zheng
Journal:  World J Surg Oncol       Date:  2022-03-04       Impact factor: 2.754

9.  Targets for Intervention? Preoperative Predictors of Postoperative Ileus After Colorectal Surgery in an Enhanced Recovery Protocol.

Authors:  Cindy Y Teng; Sara Myers; Tanya S Kenkre; Luke Doney; Wai Lok Tsang; Kathirvel Subramaniam; Stephen A Esper; Jennifer Holder-Murray
Journal:  J Gastrointest Surg       Date:  2020-11-17       Impact factor: 3.267

10.  Prolonged postoperative ileus in gastric surgery: Is there any difference between laparoscopic and open surgery?

Authors:  Wenquan Liang; Jiyang Li; Wang Zhang; Jie Liu; Mingsen Li; Yunhe Gao; Ning Wang; Jianxin Cui; Kecheng Zhang; Hongqing Xi; Bo Wei; Lin Chen
Journal:  Cancer Med       Date:  2019-08-05       Impact factor: 4.452

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