H Prosch1, L Ebner2. 1. Univ. Klinik für Radiologie und Nuklearmedizin, Medizinische Universität Wien, Allgemeines Krankenhaus Wien, Währingergürtel 18-20, 1090, Wien, Österreich. helmut.prosch@meduniwien.ac.at. 2. Universitätsinstitut für Diagnostische, Interventionelle und Pädiatrische Radiologie (DIPR), Inselspital, Universitätsspital Bern, Bern, Schweiz.
Abstract
CLINICAL/METHODICAL ISSUE: The National Lung Screening Trial (NLST) in 2011 was able to prove for the first time that screening with a low-dose CT can reduce lung carcinoma mortality by 20%. Despite the positive outcome of the NLST, there is-unlike in the USA-currently no systematic lung cancer screening in Europe. This is partly because several significantly smaller screening studies in Europe failed to show any improvement in lung cancer mortality. STANDARD RADIOLOGICAL METHODS: On the other hand, Europe's healthcare systems differ substantially from those in the United States, so that a direct transfer of US experience to Europe is not possible. For this reason, guidelines for lung cancer screening must be developed in the individual European countries to ensure that lung cancer mortality can be reduced by means of a quality-assured and cost-effective lung cancer screening. PRACTICAL RECOMMENDATIONS: The experience and the expected results of the European screening studies can provide valuable help for these purposes.
CLINICAL/METHODICAL ISSUE: The National Lung Screening Trial (NLST) in 2011 was able to prove for the first time that screening with a low-dose CT can reduce lung carcinoma mortality by 20%. Despite the positive outcome of the NLST, there is-unlike in the USA-currently no systematic lung cancer screening in Europe. This is partly because several significantly smaller screening studies in Europe failed to show any improvement in lung cancer mortality. STANDARD RADIOLOGICAL METHODS: On the other hand, Europe's healthcare systems differ substantially from those in the United States, so that a direct transfer of US experience to Europe is not possible. For this reason, guidelines for lung cancer screening must be developed in the individual European countries to ensure that lung cancer mortality can be reduced by means of a quality-assured and cost-effective lung cancer screening. PRACTICAL RECOMMENDATIONS: The experience and the expected results of the European screening studies can provide valuable help for these purposes.
Entities:
Keywords:
Cost efficacy; Health care systems; Pulmonary nodules; Risk models; Study data
Authors: Carlijn Michelle van der Aalst; Karien Anna Margaretha van den Bergh; Marc Christiaan Willemsen; Henricus Johannes de Koning; Robertus Johannes van Klaveren Journal: Thorax Date: 2010-07 Impact factor: 9.139
Authors: Denise R Aberle; Amanda M Adams; Christine D Berg; William C Black; Jonathan D Clapp; Richard M Fagerstrom; Ilana F Gareen; Constantine Gatsonis; Pamela M Marcus; JoRean D Sicks Journal: N Engl J Med Date: 2011-06-29 Impact factor: 91.245
Authors: Ugo Pastorino; Marta Rossi; Valentina Rosato; Alfonso Marchianò; Nicola Sverzellati; Carlo Morosi; Alessandra Fabbri; Carlotta Galeone; Eva Negri; Gabriella Sozzi; Giuseppe Pelosi; Carlo La Vecchia Journal: Eur J Cancer Prev Date: 2012-05 Impact factor: 2.497
Authors: Peter B Bach; Michael W Kattan; Mark D Thornquist; Mark G Kris; Ramsey C Tate; Matt J Barnett; Lillian J Hsieh; Colin B Begg Journal: J Natl Cancer Inst Date: 2003-03-19 Impact factor: 13.506
Authors: Rob J van Klaveren; Matthijs Oudkerk; Mathias Prokop; Ernst T Scholten; Kristiaan Nackaerts; Rene Vernhout; Carola A van Iersel; Karien A M van den Bergh; Susan van 't Westeinde; Carlijn van der Aalst; Erik Thunnissen; Dong Ming Xu; Ying Wang; Yingru Zhao; Hester A Gietema; Bart-Jan de Hoop; Harry J M Groen; Geertruida H de Bock; Peter van Ooijen; Carla Weenink; Johny Verschakelen; Jan-Willem J Lammers; Wim Timens; Dik Willebrand; Aryan Vink; Willem Mali; Harry J de Koning Journal: N Engl J Med Date: 2009-12-03 Impact factor: 91.245
Authors: Olaide Y Raji; Stephen W Duffy; Olorunshola F Agbaje; Stuart G Baker; David C Christiani; Adrian Cassidy; John K Field Journal: Ann Intern Med Date: 2012-08-21 Impact factor: 25.391
Authors: Maurizio Infante; Silvio Cavuto; Fabio Romano Lutman; Giorgio Brambilla; Giuseppe Chiesa; Giovanni Ceresoli; Eliseo Passera; Enzo Angeli; Maurizio Chiarenza; Giuseppe Aranzulla; Umberto Cariboni; Valentina Errico; Francesco Inzirillo; Edoardo Bottoni; Emanuele Voulaz; Marco Alloisio; Anna Destro; Massimo Roncalli; Armando Santoro; Gianluigi Ravasi Journal: Am J Respir Crit Care Med Date: 2009-06-11 Impact factor: 21.405