Fatih Alper Akcan1, Yusuf Dündar2, Hümeyra Bayram Akcan3, Derya Cebeci1, Mehmet Ali Sungur4, İlhan Ünlü1. 1. Department of Otorhinolaryngology, Düzce University School of Medicine, Düzce, Turkey. 2. Department Of Otolaryngology - Head - Neck Surgery, Wayne State University School of Medicine, Michigan, USA. 3. Clinic of Internal Medicine, Ministry of Health Atatürk Hospital, Düzce, Turkey. 4. Department of Biostatistics, Düzce University School of Medicine, Düzce, Turkey.
Abstract
OBJECTIVES: The purpose of this trial is to examine the clinical role of iron metabolism on development of Otitis media with effusion. MATERIALS AND METHODS: This prospective study was conducted in a tertiary referral center. The study group made up of children who had surgery for Otitis media with effusion (OME). Control group was comprised of children who had surgery by a pediatric surgeon for inguinal hernia repair or circumcision operations with normal ear nose throat examination. Each group was evaluated depending on the serum iron metabolism parameters. RESULTS: One-hundred-thirteen children with OME and 117 control patients were included to the study. Iron deficiency anemia was detected in 18 out of 113 patients (15.9%) in study group while there were 4 out of the 117 patients (3.4%) in control group (p:0.001).The mean hemoglobin level was 12.16 ± 1.16 in OME group and 12.93 ± 1.08 in control group (p<0.001). CONCLUSION: The current study shows the rate of iron deficiency anemia is higher in patients with OME than controls. Iron-deficiency anemia might be considered a potential risk factor for development of otitis media with effusion, and iron parameters should be evaluated in these children.
OBJECTIVES: The purpose of this trial is to examine the clinical role of iron metabolism on development of Otitis media with effusion. MATERIALS AND METHODS: This prospective study was conducted in a tertiary referral center. The study group made up of children who had surgery for Otitis media with effusion (OME). Control group was comprised of children who had surgery by a pediatric surgeon for inguinal hernia repair or circumcision operations with normal ear nose throat examination. Each group was evaluated depending on the serum iron metabolism parameters. RESULTS: One-hundred-thirteen children with OME and 117 control patients were included to the study. Iron deficiency anemia was detected in 18 out of 113 patients (15.9%) in study group while there were 4 out of the 117 patients (3.4%) in control group (p:0.001).The mean hemoglobin level was 12.16 ± 1.16 in OME group and 12.93 ± 1.08 in control group (p<0.001). CONCLUSION: The current study shows the rate of iron deficiency anemia is higher in patients with OME than controls. Iron-deficiency anemia might be considered a potential risk factor for development of otitis media with effusion, and iron parameters should be evaluated in these children.