Literature DB >> 30539326

Multiple Equilibria in a Non-smooth Epidemic Model with Medical-Resource Constraints.

Aili Wang1, Yanni Xiao2, Robert Smith3.   

Abstract

The issue of medical-resource constraints has the potential to dramatically affect disease management, especially in developing countries. We analyze a non-smooth epidemic model with nonlinear incidence rate and resource constraints, which defines a vaccination program with vaccination rate proportional to the number of susceptible individuals when this number is below the threshold level and constant otherwise. To better understand the impact of this non-smooth vaccination policy, we provide a comprehensive qualitative analysis of global dynamics for the whole parameter space. As the threshold value varies, the target model admits multistability of three regular equilibria, bistability of two regular equilibria, that of one disease-free equilibrium and one generalized endemic equilibria, and that of one disease-free equilibrium and one crossing cycle. The steady-state regimes include healthy, low epidemic and high epidemic. This suggests the key role of the threshold value, as well as the initial infection condition in disease control. Our findings demonstrate that the case number can be contained at a satisfactorily controllable level or range if eradicating it proves to be impossible.

Entities:  

Keywords:  Crossing cycle; Generalized equilibrium; Multistability; Non-smooth epidemic model; Nonlinear incidence; Resources constraints

Mesh:

Year:  2018        PMID: 30539326     DOI: 10.1007/s11538-018-00544-2

Source DB:  PubMed          Journal:  Bull Math Biol        ISSN: 0092-8240            Impact factor:   1.758


  5 in total

1.  Dynamics of a non-smooth epidemic model with three thresholds.

Authors:  Aili Wang; Yanni Xiao; Robert Smith
Journal:  Theory Biosci       Date:  2019-08-07       Impact factor: 1.919

2.  System Complexity in Influenza Infection and Vaccination: Effects upon Excess Winter Mortality.

Authors:  Rodney P Jones; Andriy Ponomarenko
Journal:  Infect Dis Rep       Date:  2022-04-21

3.  Mathematical COVID-19 model with vaccination: a case study in Saudi Arabia.

Authors:  Abeer D Algarni; Aws Ben Hamed; Monia Hamdi; Hela Elmannai; Souham Meshoul
Journal:  PeerJ Comput Sci       Date:  2022-05-13

4.  Modeling the effect of Fangcang shelter hospitals on the control of COVID-19 epidemic.

Authors:  Aili Wang; Jin Guo; Yinjiao Gong; Xueying Zhang; Rong Yan
Journal:  Math Methods Appl Sci       Date:  2022-06-10       Impact factor: 3.007

5.  Impact of Hospital Bed Shortages on the Containment of COVID-19 in Wuhan.

Authors:  Weike Zhou; Aili Wang; Xia Wang; Robert A Cheke; Yanni Xiao; Sanyi Tang
Journal:  Int J Environ Res Public Health       Date:  2020-11-18       Impact factor: 3.390

  5 in total

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