| Literature DB >> 30538397 |
Aleena Jain1, Manjusha Karegar1, Amita Joshi1, Amey Rojekar1.
Abstract
Granular cell tumours are uncommon, usually benign soft tissue tumours. They are thought to be neural, arising from Schwann cells and can occur at various sites. Their occurrence in gastrointestinal tract is rare, the commonest site being oesophagus followed by large intestine. Gastric localization is unusual. A young female presented with abdominal discomfort since 3 months. Endoscopy showed a nodule in the body of stomach. Biopsy revealed features of granular cell tumour on microscopy, which was confirmed by immunohistochemical positivity for S100 and CD68. Wide excision of the tumour was performed. At the 6-month follow-up, patient was asymptomatic. The diagnosis of gastric granular cell tumour is based on endoscopic biopsy. Unless there is histological evidence of malignancy, wide local excision is an adequate surgical treatment.Entities:
Keywords: CD 68; Endoscopy; Granular cell tumour; Immunohistochemistry; S100; Stomach
Year: 2018 PMID: 30538397 PMCID: PMC6265194 DOI: 10.1007/s13193-018-0794-y
Source DB: PubMed Journal: Indian J Surg Oncol ISSN: 0975-7651