Literature DB >> 30538381

Outcome of Bowel Resection in Women with Advanced Ovarian Carcinoma.

Ajit Sebastian1, Anitha Thomas1, Gigi Varghese2, Bijesh Yadav3, Rachel Chandy1, Abraham Peedicayil1.   

Abstract

To evaluate the mortality and morbidity related to bowel resection in women with advanced ovarian carcinoma. Retrospective case series of 47 women with stage III and IV carcinoma ovary who underwent bowel resection, over the period of 5 years from Jan 2011 to Dec 2015. The risk factors for perioperative morbidity and death were determined by regression analysis. The disease free and overall survival were determined by Kaplan-Meier plots. In this cohort, 64% (30/47) had primary debulking, 21% (10/47) had interval debulking, and 15% (7/47) had secondary debulking. The mean period of follow-up was 23 months (1 to 45 months). There were no anastomotic leaks. The commonest morbidities were relaparotomy (8.5%), surgical site infection (12%), and paralytic ileus (19%). The overall morbidity was 42.6% (20/47). The 30-day mortality was 4.2% (2/47). The recurrence rate was 51% (20/47). The overall mortality from ovarian cancer in this cohort was 40% (19/47) during the follow-up period. Stage and histology seemed to be important risk factors for morbidity. Low BMI and sub-optimal debulking were significant risk factors for recurrence and death in univariate analysis. Bowel resection, in optimally selected cases of advanced carcinoma ovary, is often required for optimal cytoreduction. It carries a reasonable peri-operative mortality and morbidity and improves overall survival.

Entities:  

Keywords:  Bowel resection; Ovarian cancer

Year:  2018        PMID: 30538381      PMCID: PMC6265198          DOI: 10.1007/s13193-018-0790-2

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  38 in total

1.  Impact of anastomotic leakage on long-term survival of patients undergoing curative resection for colorectal cancer.

Authors:  C S McArdle; D C McMillan; D J Hole
Journal:  Br J Surg       Date:  2005-09       Impact factor: 6.939

2.  Rectosigmoid resection at the time of primary cytoreduction for advanced ovarian cancer. A multi-center analysis of surgical and oncological outcomes.

Authors:  Michele Peiretti; Robert E Bristow; Ignacio Zapardiel; Melissa Gerardi; Vanna Zanagnolo; Roberto Biffi; Fabio Landoni; Luca Bocciolone; Giovanni Damiano Aletti; Angelo Maggioni
Journal:  Gynecol Oncol       Date:  2012-04-30       Impact factor: 5.482

3.  Surgical indications for combined partial rectosigmoidectomy in ovarian cancer.

Authors:  Osamu Takahashi; Naoki Sato; Yoshinori Miura; Masaki Ogawa; Toshio Fujimoto; Hidenori Tanaka; Hirokazu Sato; Toshinobu Tanaka
Journal:  J Obstet Gynaecol Res       Date:  2005-12       Impact factor: 1.730

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Journal:  Cancer       Date:  2000-01-15       Impact factor: 6.860

5.  Complete cytoreductive surgery is feasible and maximizes survival in patients with advanced epithelial ovarian cancer: a prospective study.

Authors:  S M Eisenkop; R L Friedman; H J Wang
Journal:  Gynecol Oncol       Date:  1998-05       Impact factor: 5.482

Review 6.  Imaging ovarian cancer and peritoneal metastases--current and emerging techniques.

Authors:  Stavroula Kyriazi; Stan B Kaye; Nandita M deSouza
Journal:  Nat Rev Clin Oncol       Date:  2010-04-13       Impact factor: 66.675

7.  Risk factors for anastomotic failure after total mesorectal excision of rectal cancer.

Authors:  K C M J Peeters; R A E M Tollenaar; C A M Marijnen; E Klein Kranenbarg; W H Steup; T Wiggers; H J Rutten; C J H van de Velde
Journal:  Br J Surg       Date:  2005-02       Impact factor: 6.939

8.  Pelvic drainage and other risk factors for leakage after elective anterior resection in rectal cancer patients: a prospective study of 978 patients.

Authors:  Chien Yuh Yeh; Chung Rong Changchien; Jeng-Yi Wang; Jinn-Shiun Chen; Hong Hwa Chen; Jy-Ming Chiang; Reiping Tang
Journal:  Ann Surg       Date:  2005-01       Impact factor: 12.969

9.  Multiple large bowel resections: potential risk factor for anastomotic leak.

Authors:  Eleftheria Kalogera; Sean C Dowdy; Andrea Mariani; Amy L Weaver; Giovanni Aletti; Jamie N Bakkum-Gamez; William A Cliby
Journal:  Gynecol Oncol       Date:  2013-04-08       Impact factor: 5.482

10.  Bowel surgery for epithelial ovarian cancer--an early case series.

Authors:  Y N Chia; E H Tay; D M Cheong; K W Eu; J Low; T H Ho; K L Yam
Journal:  Ann Acad Med Singapore       Date:  2003-09       Impact factor: 2.473

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  1 in total

1.  Ostomy Does Not Lead to Worse Outcomes After Bowel Resection With Ovarian Cancer: A Systematic Review.

Authors:  Xinlin He; Zhengyu Li
Journal:  Front Oncol       Date:  2022-05-23       Impact factor: 5.738

  1 in total

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