Yi Pan1, Lu Zhang2, Minghui Duan1, Hong Yang3, Duoduo Zhao1, Weifeng Li1. 1. Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. 2. Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, pumczhanglu@126.com. 3. Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Abstract
OBJECTIVE: The aim of this paper was to describe a rare case of blue rubber bleb nevus (BRBNS) with growth retardation and pubertal delay. CLINICAL PRESENTATION AND INTERVENTION: A 16-year-old boy with severe iron deficiency anemia was diagnosed with BRBNS, showing growth retardation and pubertal delay simultaneously. The patient was treated conservatively with intravenous iron therapy, and his puberty advanced gradually. CONCLUSION: Given that growth retardation and pubertal delay are rare in BRBNS patients, this case reminds us to include BRBNS in the differential diagnosis of growth retardation.
OBJECTIVE: The aim of this paper was to describe a rare case of blue rubber bleb nevus (BRBNS) with growth retardation and pubertal delay. CLINICAL PRESENTATION AND INTERVENTION: A 16-year-old boy with severe iron deficiency anemia was diagnosed with BRBNS, showing growth retardation and pubertal delay simultaneously. The patient was treated conservatively with intravenous iron therapy, and his puberty advanced gradually. CONCLUSION: Given that growth retardation and pubertal delay are rare in BRBNS patients, this case reminds us to include BRBNS in the differential diagnosis of growth retardation.
Authors: Julie Soblet; Jaakko Kangas; Marjut Nätynki; Antonella Mendola; Raphaël Helaers; Melanie Uebelhoer; Mika Kaakinen; Maria Cordisco; Anne Dompmartin; Odile Enjolras; Simon Holden; Alan D Irvine; Loshan Kangesu; Christine Léauté-Labrèze; Agustina Lanoel; Zerina Lokmic; Saskia Maas; Maeve A McAleer; Anthony Penington; Paul Rieu; Samira Syed; Carine van der Vleuten; Rosemarie Watson; Steven J Fishman; John B Mulliken; Lauri Eklund; Nisha Limaye; Laurence M Boon; Miikka Vikkula Journal: J Invest Dermatol Date: 2016-08-09 Impact factor: 8.551