| Literature DB >> 30537039 |
Najmeh Ahangari1, Saeid Kargozar1, Majid Ghayour-Mobarhan1,2,3, Francesco Baino4, Alireza Pasdar1,5, Amirhossein Sahebkar6,7, Gordon A A Ferns8, Hae-Won Kim9,10,11, Masoud Mozafari12,13,14.
Abstract
Curcumin is the principal polyphenolic compound present in turmeric with broad applications in tissue engineering and regenerative medicine. It has some important inherent properties with the potential to facilitate tissue healing, including anti-inflammatory, anti-oxidant, and antibacterial activities. Therefore, curcumin has been used for the treatment of various damaged tissues, especially wound injuries. There are different forms of curcumin, among which nano-formulations are of a great importance in regenerative medicine. It is also important to design sophisticated delivery systems for controlled/localized delivery of curcumin to the target tissues and organs. Although there are many reports on the advantages of this compound, further research is required to fully explore its clinical usage. The review describes the physicochemical and biological properties of curcumin and the current state of the evidence on its applications in tissue engineering.Entities:
Keywords: anti-inflammation; anti-oxidant; antibacterial; curcumin; scaffold; tissue engineering; tissue repair; wound healing
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Year: 2018 PMID： 30537039 DOI： 10.1002/biof.1474
Source DB: PubMed Journal: Biofactors ISSN： 0951-6433 Impact factor: 6.113