| Literature DB >> 30536647 |
Yanfen Zhang1, Ruocen Bai1, Chong Liu2, Chunyan Ma1, Xin Chen1, Jun Yang1, Dandan Sun1.
Abstract
Diabetes mellitus (DM) has become the third major chronic non-communicable disease affecting global public health, following cancer and cardiovascular and cerebrovascular diseases. Although previous studies have found a correlation between microRNA (miRNA) and the development of DM, thus far, most reviews have focused on the studies describing the changes in miRNA expression profiles and the mechanisms by which miRNAs-induce DM. However, reviews summarizing the effect of miRNA single-nucleotide polymorphisms on the developmental stages of DM and its complications are still needed. Studies on the variation of miRNAs will not only help to further understand the role that genetic factors play in DM, but will also have important implications for treatment and disease prognosis.Entities:
Keywords: MicroRNA; diabetes mellitus; diabetic complication; single-nucleotide polymorphism
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Year: 2019 PMID： 30536647 DOI： 10.1111/cge.13491
Source DB: PubMed Journal: Clin Genet ISSN： 0009-9163 Impact factor: 4.438