Literature DB >> 30536096

Induction of Functional Hepatocytes from Human iPSCs.

Taketomo Kido1, Yuta Koui2.   

Abstract

Human-induced pluripotent stem cells (iPSCs) could be a useful source for production of hepatocytes. Here, we develop protocols to generate iPSC-derived liver progenitor cells, liver sinusoidal endothelial cells (LSECs), and hepatic stellate cells (HSCs). We also establish long-term two-dimensional co-culture system to induce functional hepatocytes from iPSC-derived liver cells.

Entities:  

Keywords:  Hepatic stellate cells; Hepatocytes; Human-induced pluripotent stem cells; Liver; Liver progenitor cells; Liver sinusoidal endothelial cells

Mesh:

Year:  2019        PMID: 30536096     DOI: 10.1007/978-1-4939-8961-4_12

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  2 in total

1.  Co-culture Model for Hepatitis B Virus Infection Using iPSC-Derived Liver Progenitor Cells and Liver Sinusoidal Endothelial Cells.

Authors:  Misao Himeno; Shin-Wei Chen; Taketomo Kido
Journal:  Methods Mol Biol       Date:  2022

2.  Principles for the design of multicellular engineered living systems.

Authors:  Onur Aydin; Austin P Passaro; Ritu Raman; Samantha E Spellicy; Robert P Weinberg; Roger D Kamm; Matthew Sample; George A Truskey; Jeremiah Zartman; Roy D Dar; Sebastian Palacios; Jason Wang; Jesse Tordoff; Nuria Montserrat; Rashid Bashir; M Taher A Saif; Ron Weiss
Journal:  APL Bioeng       Date:  2022-03-02
  2 in total

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