Literature DB >> 30535971

Anticancer Potential of Syzygium Species: a Review.

Lee Kee Chua1, Chooi Ling Lim1, Anna Pick Kiong Ling1, Soi Moi Chye1, Rhun Yian Koh2.   

Abstract

Cancer is a preventable and treatable disease, however, the incidence rates are on the rise. Classical treatment modalities for cancer include surgery, radiotherapy and chemotherapy. However, these are associated with detrimental side effects such as nausea and emesis. Therefore, researchers currently vest interest in complementary and alternative medicines for cancer treatment and prevention. Plants such as Syzygium sp. are a common basis of complementary medicines due to its abundance of bioactive phytochemicals. Numerous natural compounds derived from Syzygium sp., such as phenolics, oleanolic acids, and betulinic acids, and dimethyl cardamonins, were reported to have anticancer effects. Many possess the ability to inhibit cell proliferation and induce apoptosis. In this review, we discuss the vast potential Syzygium sp. harbours as a source of anticancer natural compounds due to its abundance, easy acceptability, affordability and safety for regular consumption.

Entities:  

Keywords:  Anticancer; Bioactive compound; Syzygium species

Mesh:

Substances:

Year:  2019        PMID: 30535971     DOI: 10.1007/s11130-018-0704-z

Source DB:  PubMed          Journal:  Plant Foods Hum Nutr        ISSN: 0921-9668            Impact factor:   3.921


  7 in total

Review 1.  Therapeutic application of Carica papaya leaf extract in the management of human diseases.

Authors:  Surya P Singh; Sanjay Kumar; Sivapar V Mathan; Munendra Singh Tomar; Rishi Kant Singh; Praveen Kumar Verma; Amit Kumar; Sandeep Kumar; Rana P Singh; Arbind Acharya
Journal:  Daru       Date:  2020-05-05       Impact factor: 3.117

2.  Evaluation of the Anti-cancer Effect of Syzygium cumini Ethanolic Extract on HT-29 Colorectal Cell Line.

Authors:  Amir Khodavirdipour; Rana Zarean; Reza Safaralizadeh
Journal:  J Gastrointest Cancer       Date:  2021-06

Review 3.  Traditional uses, pharmacological activities, and phytochemical constituents of the genus Syzygium: A review.

Authors:  A B M Neshar Uddin; Farhad Hossain; A S M Ali Reza; Mst Samima Nasrin; A H M Khurshid Alam
Journal:  Food Sci Nutr       Date:  2022-03-04       Impact factor: 3.553

4.  Treatment of the bone marrow stromal stem cell supernatant by nasal administration-a new approach to EAE therapy.

Authors:  Xi Wang; Wantong Zhai; Jiahui Zhu; Wei Zhao; Xiaoyi Zou; Siying Qu; Shenyue Wang; Zhongze He; Zhaoying Li; Lingyang Wang; Bo Sun; Hulun Li
Journal:  Stem Cell Res Ther       Date:  2019-11-15       Impact factor: 6.832

Review 5.  Syzygium jambos L. Alston: An Insight Into its Phytochemistry, Traditional Uses, and Pharmacological Properties.

Authors:  Melvin Adhiambo Ochieng; Widad Ben Bakrim; Gabin Thierry M Bitchagno; Mona F Mahmoud; Mansour Sobeh
Journal:  Front Pharmacol       Date:  2022-01-24       Impact factor: 5.810

Review 6.  Targeting the JAK/STAT Signaling Pathway Using Phytocompounds for Cancer Prevention and Therapy.

Authors:  Sankhadip Bose; Sabyasachi Banerjee; Arijit Mondal; Utsab Chakraborty; Joshua Pumarol; Courtney R Croley; Anupam Bishayee
Journal:  Cells       Date:  2020-06-11       Impact factor: 6.600

Review 7.  Mechanistic insights into dimethyl cardamonin-mediated pharmacological effects: A double control of the AMPK-HMGB1 signaling axis.

Authors:  Christian Bailly; Gérard Vergoten
Journal:  Life Sci       Date:  2020-10-18       Impact factor: 5.037

  7 in total

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