Literature DB >> 30535877

Impact of preoperative wait time on survival in patients with clinical stage II/III gastric cancer.

Kenichiro Furukawa1, Tomoyuki Irino1, Rie Makuuchi1, Yusuke Koseki1, Kenichi Nakamura1, Yuhei Waki1, Keiichi Fujiya1, Hayato Omori1, Yutaka Tanizawa1, Etsuro Bando1, Taiichi Kawamura1, Masanori Terashima2.   

Abstract

BACKGROUND: Preoperative wait time is affected by various factors, and a certain time is needed before surgery. There is a concern that cancer treatment delay can lead to poor survival. The present study aimed to evaluate the impact of preoperative wait time on survival in patients with clinical stage (cStage) II/III gastric cancer.
METHODS: The study included patients with cStage II/III primary gastric cancer undergoing surgery between 2002 and 2012. Preoperative wait time was defined as the time from endoscopy for initial diagnosis to surgery. Patients were divided into the following three groups according to wait time: short wait group (≤ 30 days), intermediate wait group (> 30 and ≤ 60 days), and long wait group (> 60 and ≤ 90 days). Patient characteristics and survival were compared among the groups.
RESULTS: This study included 467 male (67%) and 229 female (33%) patients, and the median patient age was 67 years. The numbers of cStage II and III patients were 332 (48%) and 364 (52%), respectively. The median wait time was 45 days. The body mass index was lower in the short wait group than in the other groups. A shorter wait time tended to be associated with a more advanced cStage. Although survival was significantly worse in the short wait group than in the long wait group, wait time was not identified as an independent prognostic factor in multivariate analysis.
CONCLUSION: Preoperative wait time up to 90 days does not affect survival in patients with cStage II/III gastric cancer.

Entities:  

Keywords:  Gastric cancer; Preoperative wait time; Surgery; Survival

Mesh:

Year:  2018        PMID: 30535877     DOI: 10.1007/s10120-018-00910-y

Source DB:  PubMed          Journal:  Gastric Cancer        ISSN: 1436-3291            Impact factor:   7.370


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