| Literature DB >> 30535687 |
Ann-Katrin Kraeuter1,2, Paul C Guest3, Zoltán Sarnyai4,5.
Abstract
The open field test is used in studies of the neurobiological basis of anxiety and screening for novel drug targets and anxiolytic compounds. This test uses a camera to measure movement of the test animal in the peripheral and central zones of a 42 × 42 × 42 cm polyvinyl chloride box. This chapter describes a protocol for carrying out the open-field test for assessment of locomotion and anxiety-like behavior in mice.Entities:
Keywords: Anxiety; Behavior; Locomotion; Open-filed; Psychiatric disorder
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Year: 2019 PMID： 30535687 DOI： 10.1007/978-1-4939-8994-2_9
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745