Literature DB >> 30534702

Towards resolving the spatial metabolome with unambiguous molecular annotations in complex biological systems by coupling mass spectrometry imaging with structures for lossless ion manipulations.

Gabe Nagy1, Dusan Veličković, Rosalie K Chu, Alyssa A Carrell, David J Weston, Yehia M Ibrahim, Christopher R Anderton, Richard D Smith.   

Abstract

We demonstrate the coupling of liquid extraction surface analysis (LESA) to structures for lossless ion manipulations in conjunction with serpentine ultralong path with extending routing (SLIM SUPER) ion mobility-mass spectrometry (IM-MS) for the unambiguous annotation of important isomeric glycoforms in carbon-fixing communities.

Entities:  

Year:  2019        PMID： 30534702      PMCID： PMC6537888          DOI： 10.1039/c8cc07482h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Integrating ion mobility and imaging mass spectrometry for comprehensive analysis of biological tissues: A brief review and perspective.

Authors:  Emilio S Rivera; Katerina V Djambazova; Elizabeth K Neumann; Richard M Caprioli; Jeffrey M Spraggins
Journal:  J Mass Spectrom       Date:  2020-09-21       Impact factor: 1.982

2.  Bulk and Spatially Resolved Extracellular Metabolome of Free-Living Nitrogen Fixation.

Authors:  Darian N Smercina; Young-Mo Kim; Mary S Lipton; Dusan Velickovic; Kirsten S Hofmockel
Journal:  Appl Environ Microbiol       Date:  2022-06-02       Impact factor: 5.005

3.  Implementation of Ion Mobility Spectrometry-Based Separations in Structures for Lossless Ion Manipulations (SLIM).

Authors:  Adam L Hollerbach; Christopher R Conant; Gabe Nagy; Yehia M Ibrahim
Journal:  Methods Mol Biol       Date:  2022

4.  Rapid and Simultaneous Characterization of Drug Conjugation in Heavy and Light Chains of a Monoclonal Antibody Revealed by High-Resolution Ion Mobility Separations in SLIM.

Authors:  Gabe Nagy; Isaac K Attah; Christopher R Conant; Weijing Liu; Sandilya V B Garimella; Harsha P Gunawardena; Jared B Shaw; Richard D Smith; Yehia M Ibrahim
Journal:  Anal Chem       Date:  2020-03-17       Impact factor: 6.986
  4 in total

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