Paula Ferrada1, Luke Wolfe, Juan Duchesne, Gustavo P Fraga, Elizabeth Benjamin, Augustin Alvarez, Andre Campbell, Christopher Wybourn, Alberto Garcia, Carlos Morales, Julieta Correa, Bruno M Pereira, Marcelo Ribeiro, Martha Quiodettis, Gregory Peck, Juan C Salamea, Victor F Kruger, Rao R Ivatury, Thomas Scalea. 1. From the Virginia Commonwealth University (P.F., L.W., R.I.), Richmond, Virginia; Tulane University (J.D.), New Orleans, Louisiana; University of Campinas (G.P.F., B.M.P.), Campinas, Brazil; Keck School of Medicine (E.B., A.A.), University of Southern California, Los Angeles, California; University of San Francisco (A.C., C.W.), San Francisco, California; Clinical Research Center (A.G.), Fundación Valle del Lili, Cali, Colombia; Universidad de Antioquia-Hospital Universitario San Vicente Fundación (C.M.J.C.), Medellin, Colombia; Hospital Geral Grajaú-Universidade Santo Amaro (M.R.), São Paulo, Brazil; Hospital Santo Tomas (M.Q.), Cuidada de Panamá, Panamá; Robert Wood Johnson Medical School (G.P.); Hospital Vicente Corral Moscoso-Universidad del Azuay (J.C.S.), Cuenca, Ecuador; and Shock Trauma Centre (T.S.), University of Maryland, College Park, Maryland.
Abstract
INTRODUCTION: The operative management of duodenal trauma remains controversial. Our hypothesis is that a simplified operative approach could lead to better outcomes. METHODS: We conducted an international multicenter study, involving 13 centers. We performed a retrospective review from January 2007 to December of 2016. Data on demographics, mechanism of trauma, blood loss, operative time, and associated injured organs were collected. Outcomes included postoperative intra-abdominal sepsis, leak, need for unplanned surgery, length of stay, renal failure, and mortality. We used the Research Electronic Data Capture tool to store the data. Poisson regression using a backward selection method was used to identify independent predictors of mortality. RESULTS: We collected data of 372 patients with duodenal injuries. Although the duodenal trauma was complex (median Injury Severity Score [ISS], 18 [interquartile range, 2-3]; Abbreviated Injury Scale, 3.5 [3-4]; American Association for the Surgery of Trauma grade, 3 [2-3]), primary repair alone was the most common type of operative management (80%, n = 299). Overall mortality was 24%. On univariate analysis, mortality was associated with male gender, lower admission systolic blood pressure, need for transfusion before operative repair, higher intraoperative blood loss, longer operative time, renal failure requiring renal replacement therapy, higher ISS, and associated pancreatic injury. Poisson regression showed higher ISS, associated pancreatic injury, postoperative renal failure requiring renal replacement therapy, the need for preoperative transfusion, and male gender remained significant predictors of mortality. Duodenal suture line leak was statistically significantly lower, and patients had primary repair over every American Association for the Surgery of Trauma grade of injury. CONCLUSIONS: The need for transfusion prior to the operating room, associated pancreatic injuries, and postoperative renal failure are predictors of mortality for patients with duodenal injuries. Primary repair alone is a common and safe operative repair even for complex injuries when feasible. LEVEL OF EVIDENCE: Therapeutic study, level IV.
INTRODUCTION: The operative management of duodenal trauma remains controversial. Our hypothesis is that a simplified operative approach could lead to better outcomes. METHODS: We conducted an international multicenter study, involving 13 centers. We performed a retrospective review from January 2007 to December of 2016. Data on demographics, mechanism of trauma, blood loss, operative time, and associated injured organs were collected. Outcomes included postoperative intra-abdominal sepsis, leak, need for unplanned surgery, length of stay, renal failure, and mortality. We used the Research Electronic Data Capture tool to store the data. Poisson regression using a backward selection method was used to identify independent predictors of mortality. RESULTS: We collected data of 372 patients with duodenal injuries. Although the duodenal trauma was complex (median Injury Severity Score [ISS], 18 [interquartile range, 2-3]; Abbreviated Injury Scale, 3.5 [3-4]; American Association for the Surgery of Trauma grade, 3 [2-3]), primary repair alone was the most common type of operative management (80%, n = 299). Overall mortality was 24%. On univariate analysis, mortality was associated with male gender, lower admission systolic blood pressure, need for transfusion before operative repair, higher intraoperative blood loss, longer operative time, renal failure requiring renal replacement therapy, higher ISS, and associated pancreatic injury. Poisson regression showed higher ISS, associated pancreatic injury, postoperative renal failure requiring renal replacement therapy, the need for preoperative transfusion, and male gender remained significant predictors of mortality. Duodenal suture line leak was statistically significantly lower, and patients had primary repair over every American Association for the Surgery of Trauma grade of injury. CONCLUSIONS: The need for transfusion prior to the operating room, associated pancreatic injuries, and postoperative renal failure are predictors of mortality for patients with duodenal injuries. Primary repair alone is a common and safe operative repair even for complex injuries when feasible. LEVEL OF EVIDENCE: Therapeutic study, level IV.
Authors: Carlos A Ordoñez; Michael W Parra; Mauricio Millán; Yaset Caicedo; Natalia Padilla; Alberto García; María Josefa Franco; Gonzalo Aristizábal; Luis Eduardo Toro; Luis Fernando Pino; Adolfo González-Hadad; Mario Alain Herrera; José Julián Serna; Fernando Rodríguez-Holguín; Alexander Salcedo; Claudia Orlas; Mónica Guzmán-Rodríguez; Fabian Hernández; Ricardo Ferrada; Rao Ivatury Journal: Colomb Med (Cali) Date: 2021-05-03
Authors: Federico Coccolini; Leslie Kobayashi; Yoram Kluger; Ernest E Moore; Luca Ansaloni; Walt Biffl; Ari Leppaniemi; Goran Augustin; Viktor Reva; Imitiaz Wani; Andrew Kirkpatrick; Fikri Abu-Zidan; Enrico Cicuttin; Gustavo Pereira Fraga; Carlos Ordonez; Emmanuil Pikoulis; Maria Grazia Sibilla; Ron Maier; Yosuke Matsumura; Peter T Masiakos; Vladimir Khokha; Alain Chichom Mefire; Rao Ivatury; Francesco Favi; Vassil Manchev; Massimo Sartelli; Fernando Machado; Junichi Matsumoto; Massimo Chiarugi; Catherine Arvieux; Fausto Catena; Raul Coimbra Journal: World J Emerg Surg Date: 2019-12-11 Impact factor: 5.469