Shane W Goodwin1, Mark A Ferro2, Kathy N Speechley3. 1. School of Public Health and Health Systems, University of Waterloo, Canada. Electronic address: sgoodwi6@uwo.ca. 2. School of Public Health and Health Systems, University of Waterloo, Canada. 3. Department of Paediatrics, Western University, Canada; Department of Epidemiology and Biostatistics, Western University, Canada; Children's Health Research Institute, Lawson Health Research Institute, London, Ontario, Canada.
Abstract
OBJECTIVE: The aim of this study was to assess measurement equivalence in the 16-item short-form Quality of Life in Childhood Epilepsy Questionnaire (QOLCE-16) across age, sex, and time in a sample of children with newly diagnosed epilepsy. METHODS: Data came from 373 children participating in the Health-related Quality of Life in Children with Epilepsy Study (HERQULES), a multicenter prospective cohort study. Measurement equivalence was assessed using multigroup confirmatory factor analysis methods. Comparison groups were stratified by age (4-7 years vs. 8-12 years), sex (male vs. female), and time (at diagnosis vs. 24 months postdiagnosis). RESULTS: The QOLCE-16 demonstrated measurement equivalence at the level of strict invariance for each comparison group tested - age: χ2 (3, 274) = 429.6, p < 0.001; comparative fit index (CFI) = 0.985; root mean square error of approximation (RMSEA) = 0.056 (0.046, 0.066); sex: χ2 (3, 271) = 430.5, p < 0.001; CFI = 0.984; RMSEA = 0.057 (0.047, 0.067); and time: χ2 (3, 269) = 566.4, p < 0.001; CFI = 0.985; RMSEA = 0.059 (0.052, 0.066). SIGNIFICANCE: The findings provide support for the robust psychometric profile of the QOLCE-16 as a reliable and valid measure of health-related quality of life for children with epilepsy. Demonstrating good properties and a multidimensional structure, the QOLCE-16 is an appropriate short measure for both clinicians and researchers wanting to obtain health-related quality of life information on children with epilepsy.
OBJECTIVE: The aim of this study was to assess measurement equivalence in the 16-item short-form Quality of Life in Childhood Epilepsy Questionnaire (QOLCE-16) across age, sex, and time in a sample of children with newly diagnosed epilepsy. METHODS: Data came from 373 children participating in the Health-related Quality of Life in Children with Epilepsy Study (HERQULES), a multicenter prospective cohort study. Measurement equivalence was assessed using multigroup confirmatory factor analysis methods. Comparison groups were stratified by age (4-7 years vs. 8-12 years), sex (male vs. female), and time (at diagnosis vs. 24 months postdiagnosis). RESULTS: The QOLCE-16 demonstrated measurement equivalence at the level of strict invariance for each comparison group tested - age: χ2 (3, 274) = 429.6, p < 0.001; comparative fit index (CFI) = 0.985; root mean square error of approximation (RMSEA) = 0.056 (0.046, 0.066); sex: χ2 (3, 271) = 430.5, p < 0.001; CFI = 0.984; RMSEA = 0.057 (0.047, 0.067); and time: χ2 (3, 269) = 566.4, p < 0.001; CFI = 0.985; RMSEA = 0.059 (0.052, 0.066). SIGNIFICANCE: The findings provide support for the robust psychometric profile of the QOLCE-16 as a reliable and valid measure of health-related quality of life for children with epilepsy. Demonstrating good properties and a multidimensional structure, the QOLCE-16 is an appropriate short measure for both clinicians and researchers wanting to obtain health-related quality of life information on children with epilepsy.
Authors: Klajdi Puka; Karen Bax; Andrea Andrade; Margo Devries-Rizzo; Hema Gangam; Simon Levin; Maryam N Nouri; Asuri N Prasad; Mary Secco; Guangyong Zou; Kathy N Speechley Journal: Trials Date: 2020-11-11 Impact factor: 2.279
Authors: Ping Tang; Qunfeng Lu; Yinghui Wu; Lin Wang; Wenjuan Tang; Yan Jiang; Liling Yang; Jianlin Ji; Xiaomin Sun; Jingmin Sun; Jie Yang Journal: Health Qual Life Outcomes Date: 2022-03-28 Impact factor: 3.186