Literature DB >> 30521319

Key Characteristics Approach to Carcinogenic Hazard Identification.

Kathryn Z Guyton1, Linda Rieswijk2, Amy Wang3, Weihsueh A Chiu4, Martyn T Smith2.   

Abstract

Evaluating carcinogenic mechanisms is a challenging part of hazard identification, as mechanistic data are both voluminous and diverse. An evaluation approach based on 10 key characteristics of human carcinogens provides a holistic and unbiased way to tackle this challenge.

Entities:  

Mesh：

Substances：

Year:  2018        PMID： 30521319      PMCID： PMC6424613          DOI： 10.1021/acs.chemrestox.8b00321

Source DB:  PubMed          Journal:  Chem Res Toxicol        ISSN： 0893-228X            Impact factor:   3.739


  4 in total

Review 1.  Improving prediction of chemical carcinogenicity by considering multiple mechanisms and applying toxicogenomic approaches.

Authors:  Kathryn Z Guyton; Amy D Kyle; Jiri Aubrecht; Vincent J Cogliano; David A Eastmond; Marc Jackson; Nagalakshmi Keshava; Martha S Sandy; Babasaheb Sonawane; Luoping Zhang; Michael D Waters; Martyn T Smith
Journal:  Mutat Res       Date:  2008-11-01       Impact factor: 2.433

Review 2.  Hallmarks of cancer: the next generation.

Authors:  Douglas Hanahan; Robert A Weinberg
Journal:  Cell       Date:  2011-03-04       Impact factor: 41.582

3.  Application of the key characteristics of carcinogens in cancer hazard identification.

Authors:  Kathryn Z Guyton; Ivan Rusyn; Weihsueh A Chiu; Denis E Corpet; Martin van den Berg; Matthew K Ross; David C Christiani; Frederick A Beland; Martyn T Smith
Journal:  Carcinogenesis       Date:  2018-04-05       Impact factor: 4.944

4.  Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis.

Authors:  Martyn T Smith; Kathryn Z Guyton; Catherine F Gibbons; Jason M Fritz; Christopher J Portier; Ivan Rusyn; David M DeMarini; Jane C Caldwell; Robert J Kavlock; Paul F Lambert; Stephen S Hecht; John R Bucher; Bernard W Stewart; Robert A Baan; Vincent J Cogliano; Kurt Straif
Journal:  Environ Health Perspect       Date:  2015-11-24       Impact factor: 9.031
  4 in total
  8 in total

1.  Development and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing.

Authors:  Xilin Li; Si Chen; Xiaoqing Guo; Qiangen Wu; Ji-Eun Seo; Lei Guo; Mugimane G Manjanatha; Tong Zhou; Kristine L Witt; Nan Mei
Journal:  Toxicol Sci       Date:  2020-06-01       Impact factor: 4.849

2.  Assessment of Mechanistic Data for Hexavalent Chromium-Induced Rodent Intestinal Cancer Using the Key Characteristics of Carcinogens.

Authors:  Grace A Chappell; Daniele S Wikoff; Chad M Thompson
Journal:  Toxicol Sci       Date:  2021-02-26       Impact factor: 4.849

3.  Signs of carcinogenicity induced by parathion, malathion, and estrogen in human breast epithelial cells (Review).

Authors:  Gloria M Calaf; Tammy C Bleak; Debasish Roy
Journal:  Oncol Rep       Date:  2021-03-02       Impact factor: 3.906

4.  Key Characteristics of Cardiovascular Toxicants.

Authors:  Lars Lind; Jesus A Araujo; Aaron Barchowsky; Scott Belcher; Brian R Berridge; Nipavan Chiamvimonvat; Weihsueh A Chiu; Vincent J Cogliano; Sarah Elmore; Aimen K Farraj; Aldrin V Gomes; Cliona M McHale; Kathleen B Meyer-Tamaki; Nikki Gillum Posnack; Hugo M Vargas; Xi Yang; Lauren Zeise; Changcheng Zhou; Martyn T Smith
Journal:  Environ Health Perspect       Date:  2021-09-24       Impact factor: 9.031

5.  Mechanistic Interrogation of Cell Transformation In Vitro: The Transformics Assay as an Exemplar of Oncotransformation.

Authors:  Gelsomina Pillo; Maria Grazia Mascolo; Cristina Zanzi; Francesca Rotondo; Stefania Serra; Francesco Bortone; Sandro Grilli; Monica Vaccari; Miriam N Jacobs; Annamaria Colacci
Journal:  Int J Mol Sci       Date:  2022-07-09       Impact factor: 6.208

6.  The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them.

Authors:  Martyn T Smith; Kathryn Z Guyton; Nicole Kleinstreuer; Alexandre Borrel; Andres Cardenas; Weihsueh A Chiu; Dean W Felsher; Catherine F Gibbons; William H Goodson; Keith A Houck; Agnes B Kane; Michele A La Merrill; Herve Lebrec; Leroy Lowe; Cliona M McHale; Sheroy Minocherhomji; Linda Rieswijk; Martha S Sandy; Hideko Sone; Amy Wang; Luoping Zhang; Lauren Zeise; Mark Fielden
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2020-03-09       Impact factor: 4.254

7.  Application of the Food Quality Protection Act children's health safety factor in the U.S. EPA pesticide risk assessments.

Authors:  Olga V Naidenko
Journal:  Environ Health       Date:  2020-02-10       Impact factor: 5.984

8.  The IARC Monographs: Updated Procedures for Modern and Transparent Evidence Synthesis in Cancer Hazard Identification.

Authors:  Jonathan M Samet; Weihsueh A Chiu; Vincent Cogliano; Jennifer Jinot; David Kriebel; Ruth M Lunn; Frederick A Beland; Lisa Bero; Patience Browne; Lin Fritschi; Jun Kanno; Dirk W Lachenmeier; Qing Lan; Gérard Lasfargues; Frank Le Curieux; Susan Peters; Pamela Shubat; Hideko Sone; Mary C White; Jon Williamson; Marianna Yakubovskaya; Jack Siemiatycki; Paul A White; Kathryn Z Guyton; Mary K Schubauer-Berigan; Amy L Hall; Yann Grosse; Véronique Bouvard; Lamia Benbrahim-Tallaa; Fatiha El Ghissassi; Béatrice Lauby-Secretan; Bruce Armstrong; Rodolfo Saracci; Jiri Zavadil; Kurt Straif; Christopher P Wild
Journal:  J Natl Cancer Inst       Date:  2020-01-01       Impact factor: 13.506
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.