James Lock1, Daniel Le Grange2,3. 1. Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California. 2. Department of Psychiatry and UCSF Weill Institute for Neurosciences, University of California, San Francisco, California. 3. Department of Psychiatry and Behavioral Neuroscience, Emeritus, The University of Chicago, Chicago, Illinois.
Abstract
OBJECTIVE: Family therapy has long been advocated as an effective intervention for eating disorders. A specific form of family therapy, one that utilizes family resources, has proven especially effective for adolescents with anorexia or bulimia nervosa (AN and BN). First developed in London, a behaviorally focused adaptation, called family-based treatment (FBT), has been manualized and systematically studied in six randomized clinical trials for adolescent AN and two for adolescent BN. METHOD: This Commentary focuses on manualized FBT; what we know, what we do not know (yet), and what we hope for. RESULTS: We do know that efficacy data for FBT, especially adolescent AN, are quite robust, even though remission rates remain elusive for more than half of all cases. While preliminary, moderators of FBT for adolescent AN have been identified and could aid us in determining the most (or least) responsive patient groups. And weight gain (∼2.5kg) by week four has been confirmed as an early predictor of remission at end-of-treatment. What we do not know, yet, is whether specific adaptations to manualized FBT will confer improved remission rates. DISCUSSION: Finally, and in terms of what is hoped for, we highlight the promise of improved access, dissemination, and implementation of FBT.
OBJECTIVE: Family therapy has long been advocated as an effective intervention for eating disorders. A specific form of family therapy, one that utilizes family resources, has proven especially effective for adolescents with anorexia or bulimia nervosa (AN and BN). First developed in London, a behaviorally focused adaptation, called family-based treatment (FBT), has been manualized and systematically studied in six randomized clinical trials for adolescent AN and two for adolescent BN. METHOD: This Commentary focuses on manualized FBT; what we know, what we do not know (yet), and what we hope for. RESULTS: We do know that efficacy data for FBT, especially adolescent AN, are quite robust, even though remission rates remain elusive for more than half of all cases. While preliminary, moderators of FBT for adolescent AN have been identified and could aid us in determining the most (or least) responsive patient groups. And weight gain (∼2.5kg) by week four has been confirmed as an early predictor of remission at end-of-treatment. What we do not know, yet, is whether specific adaptations to manualized FBT will confer improved remission rates. DISCUSSION: Finally, and in terms of what is hoped for, we highlight the promise of improved access, dissemination, and implementation of FBT.
Authors: Kelsey E Hagan; Brittany E Matheson; Nandini Datta; Alexa M L'Insalata; Z Ayotola Onipede; Sasha Gorrell; Sangeeta Mondal; Cara M Bohon; Daniel Le Grange; James D Lock Journal: Psychol Med Date: 2021-05-06 Impact factor: 7.723
Authors: Jessica A Lin; Grace Jhe; Julia A Vitagliano; Carly E Milliren; Rebecca Spigel; Elizabeth R Woods; Sara F Forman; Tracy K Richmond Journal: J Eat Disord Date: 2021-05-17